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dc.creatorSavić, Ivan
dc.creatorNikolić, Ivana Lj.
dc.creatorSavić-Gajić, Ivana
dc.creatorKundaković, Tatjana
dc.date.accessioned2019-09-02T12:11:41Z
dc.date.available2019-09-02T12:11:41Z
dc.date.issued2019
dc.identifier.issn0149-6395
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/3362
dc.description.abstractThe aim of study was to model and optimize the extraction of polyphenols and flavonoids with expressed antioxidant activity from chickpea seeds using a central composite design. The optimal extraction conditions were the extraction time of 145.5 min, ethanol concentration of 83.7% and liquid-to-solid ratio of 24.9 (expressed as cm(3) per g). The content of total polyphenol and flavonoid was 2.75 g gallic acid equivalent per kilogram of the dried extract and 0.147 g rutin equivalent per kilogram of the dried extract, respectively. Using 2,2-diphenyl-1-picrylhydrazyl assay, it was found that the optimal extract had the IC50 of 1.55 mg cm(-3).en
dc.publisherTaylor & Francis Inc, Philadelphia
dc.relationinfo:eu-repo/grantAgreement/MESTD/Technological Development (TD or TR)/34012/RS//
dc.rightsrestrictedAccess
dc.sourceSolid State Ionics
dc.subjectChickpeaen
dc.subjecttotal polyphenolen
dc.subjecttotal flavonoiden
dc.subjectantioxidant activityen
dc.subjectcentral composite designen
dc.titleModeling and optimization of bioactive compounds from chickpea seeds (Cicer arietinum L)en
dc.typearticle
dc.rights.licenseARR
dcterms.abstractСавић-Гајић, Ивана; Николић, Ивана Љ.; Савић, Иван М.; Кундаковић, Татјана;
dc.citation.volume54
dc.citation.issue5
dc.citation.spage837
dc.citation.epage846
dc.citation.other54(5): 837-846
dc.citation.rankM23
dc.identifier.wos000464574300018
dc.identifier.doi10.1080/01496395.2018.1520720
dc.identifier.scopus2-s2.0-85053510649
dc.identifier.rcubconv_4349
dc.type.versionpublishedVersion


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