The retention behavior of bifonazole, clotrimazole, fenticonazole, fluconazole, ketoconazole, miconazole, metronidazole, and itraconazole, widely used antimycotic drugs have been determined by TLC by use of the binary mobile phases acetone-n-hexane, methanol-toluene, and methyl ethyl ketone-toluene containing different amounts of organic modifier. Hydrophobicity was established from the linear relationships between the solute R-M values and the concentration of organic modifier. Calculated values of R-M(0) and C-0 were considered for application in QSAR studies of the antimycotics.
Source:
Journal of Planar Chromatography - Modern TLC, 2002, 15, 6, 414-417
TY - JOUR
AU - Aleksić, Mirjana
AU - Erić, Slavica
AU - Agbaba, Danica
AU - Odović, Jadranka
AU - Milojković-Opsenica, Dušanka
AU - Tesić, I
PY - 2002
UR - http://farfar.pharmacy.bg.ac.rs/handle/123456789/342
AB - The retention behavior of bifonazole, clotrimazole, fenticonazole, fluconazole, ketoconazole, miconazole, metronidazole, and itraconazole, widely used antimycotic drugs have been determined by TLC by use of the binary mobile phases acetone-n-hexane, methanol-toluene, and methyl ethyl ketone-toluene containing different amounts of organic modifier. Hydrophobicity was established from the linear relationships between the solute R-M values and the concentration of organic modifier. Calculated values of R-M(0) and C-0 were considered for application in QSAR studies of the antimycotics.
PB - Research Inst Medicinal Plants, Budakalasz
T2 - Journal of Planar Chromatography - Modern TLC
T1 - Estimation of the hydrophobicity of antimycotic compounds by planar chromatography
VL - 15
IS - 6
SP - 414
EP - 417
DO - 10.1556/JPC.15.2002.6.4
ER -
@article{
author = "Aleksić, Mirjana and Erić, Slavica and Agbaba, Danica and Odović, Jadranka and Milojković-Opsenica, Dušanka and Tesić, I",
year = "2002",
url = "http://farfar.pharmacy.bg.ac.rs/handle/123456789/342",
abstract = "The retention behavior of bifonazole, clotrimazole, fenticonazole, fluconazole, ketoconazole, miconazole, metronidazole, and itraconazole, widely used antimycotic drugs have been determined by TLC by use of the binary mobile phases acetone-n-hexane, methanol-toluene, and methyl ethyl ketone-toluene containing different amounts of organic modifier. Hydrophobicity was established from the linear relationships between the solute R-M values and the concentration of organic modifier. Calculated values of R-M(0) and C-0 were considered for application in QSAR studies of the antimycotics.",
publisher = "Research Inst Medicinal Plants, Budakalasz",
journal = "Journal of Planar Chromatography - Modern TLC",
title = "Estimation of the hydrophobicity of antimycotic compounds by planar chromatography",
volume = "15",
number = "6",
pages = "414-417",
doi = "10.1556/JPC.15.2002.6.4"
}
Aleksić, M., Erić, S., Agbaba, D., Odović, J., Milojković-Opsenica, D.,& Tesić, I. (2002). Estimation of the hydrophobicity of antimycotic compounds by planar chromatography.
Journal of Planar Chromatography - Modern TLC
Research Inst Medicinal Plants, Budakalasz., 15(6), 414-417.
https://doi.org/10.1556/JPC.15.2002.6.4
Aleksić M, Erić S, Agbaba D, Odović J, Milojković-Opsenica D, Tesić I. Estimation of the hydrophobicity of antimycotic compounds by planar chromatography. Journal of Planar Chromatography - Modern TLC. 2002;15(6):414-417
Aleksić Mirjana, Erić Slavica, Agbaba Danica, Odović Jadranka, Milojković-Opsenica Dušanka, Tesić I, "Estimation of the hydrophobicity of antimycotic compounds by planar chromatography" Journal of Planar Chromatography - Modern TLC, 15, no. 6 (2002):414-417,
https://doi.org/10.1556/JPC.15.2002.6.4 .
