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Estimation of the hydrophobicity of antimycotic compounds by planar chromatography

Authorized Users Only
2002
Authors
Aleksić, Mirjana
Erić, Slavica
Agbaba, Danica
Odović, Jadranka
Milojković-Opsenica, Dušanka
Tesić, I
Article (Published version)
Metadata
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Abstract
The retention behavior of bifonazole, clotrimazole, fenticonazole, fluconazole, ketoconazole, miconazole, metronidazole, and itraconazole, widely used antimycotic drugs have been determined by TLC by use of the binary mobile phases acetone-n-hexane, methanol-toluene, and methyl ethyl ketone-toluene containing different amounts of organic modifier. Hydrophobicity was established from the linear relationships between the solute R-M values and the concentration of organic modifier. Calculated values of R-M(0) and C-0 were considered for application in QSAR studies of the antimycotics.
Source:
Journal of Planar Chromatography - Modern TLC, 2002, 15, 6, 414-417
Publisher:
  • Research Inst Medicinal Plants, Budakalasz

DOI: 10.1556/JPC.15.2002.6.4

ISSN: 0933-4173

WoS: 000180914000004

Scopus: 2-s2.0-0036874491
[ Google Scholar ]
20
14
URI
http://farfar.pharmacy.bg.ac.rs/handle/123456789/342
Collections
  • Radovi istraživača / Researchers’ publications
Institution
Pharmacy
TY  - JOUR
AU  - Aleksić, Mirjana
AU  - Erić, Slavica
AU  - Agbaba, Danica
AU  - Odović, Jadranka
AU  - Milojković-Opsenica, Dušanka
AU  - Tesić, I
PY  - 2002
UR  - http://farfar.pharmacy.bg.ac.rs/handle/123456789/342
AB  - The retention behavior of bifonazole, clotrimazole, fenticonazole, fluconazole, ketoconazole, miconazole, metronidazole, and itraconazole, widely used antimycotic drugs have been determined by TLC by use of the binary mobile phases acetone-n-hexane, methanol-toluene, and methyl ethyl ketone-toluene containing different amounts of organic modifier. Hydrophobicity was established from the linear relationships between the solute R-M values and the concentration of organic modifier. Calculated values of R-M(0) and C-0 were considered for application in QSAR studies of the antimycotics.
PB  - Research Inst Medicinal Plants, Budakalasz
T2  - Journal of Planar Chromatography - Modern TLC
T1  - Estimation of the hydrophobicity of antimycotic compounds by planar chromatography
VL  - 15
IS  - 6
SP  - 414
EP  - 417
DO  - 10.1556/JPC.15.2002.6.4
ER  - 
@article{
author = "Aleksić, Mirjana and Erić, Slavica and Agbaba, Danica and Odović, Jadranka and Milojković-Opsenica, Dušanka and Tesić, I",
year = "2002",
url = "http://farfar.pharmacy.bg.ac.rs/handle/123456789/342",
abstract = "The retention behavior of bifonazole, clotrimazole, fenticonazole, fluconazole, ketoconazole, miconazole, metronidazole, and itraconazole, widely used antimycotic drugs have been determined by TLC by use of the binary mobile phases acetone-n-hexane, methanol-toluene, and methyl ethyl ketone-toluene containing different amounts of organic modifier. Hydrophobicity was established from the linear relationships between the solute R-M values and the concentration of organic modifier. Calculated values of R-M(0) and C-0 were considered for application in QSAR studies of the antimycotics.",
publisher = "Research Inst Medicinal Plants, Budakalasz",
journal = "Journal of Planar Chromatography - Modern TLC",
title = "Estimation of the hydrophobicity of antimycotic compounds by planar chromatography",
volume = "15",
number = "6",
pages = "414-417",
doi = "10.1556/JPC.15.2002.6.4"
}
Aleksić M, Erić S, Agbaba D, Odović J, Milojković-Opsenica D, Tesić I. Estimation of the hydrophobicity of antimycotic compounds by planar chromatography. Journal of Planar Chromatography - Modern TLC. 2002;15(6):414-417
Aleksić, M., Erić, S., Agbaba, D., Odović, J., Milojković-Opsenica, D.,& Tesić, I. (2002). Estimation of the hydrophobicity of antimycotic compounds by planar chromatography.
Journal of Planar Chromatography - Modern TLCResearch Inst Medicinal Plants, Budakalasz., 15(6), 414-417.
https://doi.org/10.1556/JPC.15.2002.6.4
Aleksić Mirjana, Erić Slavica, Agbaba Danica, Odović Jadranka, Milojković-Opsenica Dušanka, Tesić I, "Estimation of the hydrophobicity of antimycotic compounds by planar chromatography" 15, no. 6 (2002):414-417,
https://doi.org/10.1556/JPC.15.2002.6.4 .

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