Estimation of the hydrophobicity of antimycotic compounds by planar chromatography
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2002
Authors
Aleksić, MirjanaErić, Slavica
Agbaba, Danica
Odović, Jadranka
Milojković-Opsenica, Dušanka
Tesić, I
Article (Published version)
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The retention behavior of bifonazole, clotrimazole, fenticonazole, fluconazole, ketoconazole, miconazole, metronidazole, and itraconazole, widely used antimycotic drugs have been determined by TLC by use of the binary mobile phases acetone-n-hexane, methanol-toluene, and methyl ethyl ketone-toluene containing different amounts of organic modifier. Hydrophobicity was established from the linear relationships between the solute R-M values and the concentration of organic modifier. Calculated values of R-M(0) and C-0 were considered for application in QSAR studies of the antimycotics.
Source:
Journal of Planar Chromatography - Modern TLC, 2002, 15, 6, 414-417Publisher:
- Research Inst Medicinal Plants, Budakalasz
DOI: 10.1556/JPC.15.2002.6.4
ISSN: 0933-4173
WoS: 000180914000004
Scopus: 2-s2.0-0036874491
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PharmacyTY - JOUR AU - Aleksić, Mirjana AU - Erić, Slavica AU - Agbaba, Danica AU - Odović, Jadranka AU - Milojković-Opsenica, Dušanka AU - Tesić, I PY - 2002 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/342 AB - The retention behavior of bifonazole, clotrimazole, fenticonazole, fluconazole, ketoconazole, miconazole, metronidazole, and itraconazole, widely used antimycotic drugs have been determined by TLC by use of the binary mobile phases acetone-n-hexane, methanol-toluene, and methyl ethyl ketone-toluene containing different amounts of organic modifier. Hydrophobicity was established from the linear relationships between the solute R-M values and the concentration of organic modifier. Calculated values of R-M(0) and C-0 were considered for application in QSAR studies of the antimycotics. PB - Research Inst Medicinal Plants, Budakalasz T2 - Journal of Planar Chromatography - Modern TLC T1 - Estimation of the hydrophobicity of antimycotic compounds by planar chromatography VL - 15 IS - 6 SP - 414 EP - 417 DO - 10.1556/JPC.15.2002.6.4 ER -
@article{ author = "Aleksić, Mirjana and Erić, Slavica and Agbaba, Danica and Odović, Jadranka and Milojković-Opsenica, Dušanka and Tesić, I", year = "2002", abstract = "The retention behavior of bifonazole, clotrimazole, fenticonazole, fluconazole, ketoconazole, miconazole, metronidazole, and itraconazole, widely used antimycotic drugs have been determined by TLC by use of the binary mobile phases acetone-n-hexane, methanol-toluene, and methyl ethyl ketone-toluene containing different amounts of organic modifier. Hydrophobicity was established from the linear relationships between the solute R-M values and the concentration of organic modifier. Calculated values of R-M(0) and C-0 were considered for application in QSAR studies of the antimycotics.", publisher = "Research Inst Medicinal Plants, Budakalasz", journal = "Journal of Planar Chromatography - Modern TLC", title = "Estimation of the hydrophobicity of antimycotic compounds by planar chromatography", volume = "15", number = "6", pages = "414-417", doi = "10.1556/JPC.15.2002.6.4" }
Aleksić, M., Erić, S., Agbaba, D., Odović, J., Milojković-Opsenica, D.,& Tesić, I.. (2002). Estimation of the hydrophobicity of antimycotic compounds by planar chromatography. in Journal of Planar Chromatography - Modern TLC Research Inst Medicinal Plants, Budakalasz., 15(6), 414-417. https://doi.org/10.1556/JPC.15.2002.6.4
Aleksić M, Erić S, Agbaba D, Odović J, Milojković-Opsenica D, Tesić I. Estimation of the hydrophobicity of antimycotic compounds by planar chromatography. in Journal of Planar Chromatography - Modern TLC. 2002;15(6):414-417. doi:10.1556/JPC.15.2002.6.4 .
Aleksić, Mirjana, Erić, Slavica, Agbaba, Danica, Odović, Jadranka, Milojković-Opsenica, Dušanka, Tesić, I, "Estimation of the hydrophobicity of antimycotic compounds by planar chromatography" in Journal of Planar Chromatography - Modern TLC, 15, no. 6 (2002):414-417, https://doi.org/10.1556/JPC.15.2002.6.4 . .