Furo- and pyranocoumarins from plant species Angelica silvestris and Peucedanum austriacum

Abstract

An investigation of the coumarin content of plant species Angelica silvestris (roots and fruits) and Peucedanum austriacum (Jacq.) Koch (roots), both belonging to the family Apiaceae is reported. A. silvestris contained only linear furocoumarins (four in the roots and five in the fruits), two of them (heraclenol and heraclenin) found for the first time in this species. The photoactive compound bergapten (also known as 5-methoxypsoralen) was also among the isolated coumarins. In P. austriacum only reduced (dihydro) coumarins were detected (four compunds): linear dihydrofurocoumarins, deltoin and sekorin, an angular dihydrofurocoumarin, zosimin and a linear dihydropyranoeoumarin, agasyllin. None of them has been found before in this plant species.