Cadmium (Cd), one of the most important environmental pollutants, can cause a number of toxic effects. These effects are the result of more than one mechanisms of toxicity, all interrelated in their complexity. Thus, it is difficult to identify a fine line between these mechanisms of Cd toxicity, making their understanding highly complicated. The most important mechanisms by which Cd manifests its toxic effects include changes in gene expression and inhibition of damaged DNA repair, interference of apoptosis and autophagy, oxidative stress, and interaction with bioelements. In this review, we will give a brief overview of the recent developments and findings on the most relevant general and specific mechanisms and molecular pathways of Cd toxicity.
TY - JOUR
AU - Đukić-Ćosić, Danijela
AU - Baralić, Katarina
AU - Javorac, Dragana
AU - Buha-Đorđević, Aleksandra
AU - Bulat, Zorica
PY - 2020
UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3511
AB - Cadmium (Cd), one of the most important environmental pollutants, can cause a number of toxic effects. These effects are the result of more than one mechanisms of toxicity, all interrelated in their complexity. Thus, it is difficult to identify a fine line between these mechanisms of Cd toxicity, making their understanding highly complicated. The most important mechanisms by which Cd manifests its toxic effects include changes in gene expression and inhibition of damaged DNA repair, interference of apoptosis and autophagy, oxidative stress, and interaction with bioelements. In this review, we will give a brief overview of the recent developments and findings on the most relevant general and specific mechanisms and molecular pathways of Cd toxicity.
T2 - Current Opinion in Toxicology
T1 - An overview of molecular mechanisms in cadmium toxicity
VL - 19
SP - 56
EP - 62
DO - 10.1016/j.cotox.2019.12.002
ER -
@article{
author = "Đukić-Ćosić, Danijela and Baralić, Katarina and Javorac, Dragana and Buha-Đorđević, Aleksandra and Bulat, Zorica",
year = "2020",
abstract = "Cadmium (Cd), one of the most important environmental pollutants, can cause a number of toxic effects. These effects are the result of more than one mechanisms of toxicity, all interrelated in their complexity. Thus, it is difficult to identify a fine line between these mechanisms of Cd toxicity, making their understanding highly complicated. The most important mechanisms by which Cd manifests its toxic effects include changes in gene expression and inhibition of damaged DNA repair, interference of apoptosis and autophagy, oxidative stress, and interaction with bioelements. In this review, we will give a brief overview of the recent developments and findings on the most relevant general and specific mechanisms and molecular pathways of Cd toxicity.",
journal = "Current Opinion in Toxicology",
title = "An overview of molecular mechanisms in cadmium toxicity",
volume = "19",
pages = "56-62",
doi = "10.1016/j.cotox.2019.12.002"
}
Đukić-Ćosić, D., Baralić, K., Javorac, D., Buha-Đorđević, A.,& Bulat, Z.. (2020). An overview of molecular mechanisms in cadmium toxicity. in Current Opinion in Toxicology, 19, 56-62.
https://doi.org/10.1016/j.cotox.2019.12.002
Đukić-Ćosić D, Baralić K, Javorac D, Buha-Đorđević A, Bulat Z. An overview of molecular mechanisms in cadmium toxicity. in Current Opinion in Toxicology. 2020;19:56-62.
doi:10.1016/j.cotox.2019.12.002 .
Đukić-Ćosić, Danijela, Baralić, Katarina, Javorac, Dragana, Buha-Đorđević, Aleksandra, Bulat, Zorica, "An overview of molecular mechanisms in cadmium toxicity" in Current Opinion in Toxicology, 19 (2020):56-62,
https://doi.org/10.1016/j.cotox.2019.12.002 . .
