An overview of molecular mechanisms in cadmium toxicity
Само за регистроване кориснике
2020
Аутори
Đukić-Ćosić, DanijelaBaralić, Katarina
Javorac, Dragana
Buha-Đorđević, Aleksandra
Bulat, Zorica
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Cadmium (Cd), one of the most important environmental pollutants, can cause a number of toxic effects. These effects are the result of more than one mechanisms of toxicity, all interrelated in their complexity. Thus, it is difficult to identify a fine line between these mechanisms of Cd toxicity, making their understanding highly complicated. The most important mechanisms by which Cd manifests its toxic effects include changes in gene expression and inhibition of damaged DNA repair, interference of apoptosis and autophagy, oxidative stress, and interaction with bioelements. In this review, we will give a brief overview of the recent developments and findings on the most relevant general and specific mechanisms and molecular pathways of Cd toxicity.
Кључне речи:
Apoptosis / Autophagy / Bioelements / Cadmium / Gene relation / Oxidative stressИзвор:
Current Opinion in Toxicology, 2020, 19, 56-62Финансирање / пројекти:
DOI: 10.1016/j.cotox.2019.12.002
ISSN: 2468-2020
WoS: 000531649300011
Scopus: 2-s2.0-85077917808
Институција/група
PharmacyTY - JOUR AU - Đukić-Ćosić, Danijela AU - Baralić, Katarina AU - Javorac, Dragana AU - Buha-Đorđević, Aleksandra AU - Bulat, Zorica PY - 2020 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3511 AB - Cadmium (Cd), one of the most important environmental pollutants, can cause a number of toxic effects. These effects are the result of more than one mechanisms of toxicity, all interrelated in their complexity. Thus, it is difficult to identify a fine line between these mechanisms of Cd toxicity, making their understanding highly complicated. The most important mechanisms by which Cd manifests its toxic effects include changes in gene expression and inhibition of damaged DNA repair, interference of apoptosis and autophagy, oxidative stress, and interaction with bioelements. In this review, we will give a brief overview of the recent developments and findings on the most relevant general and specific mechanisms and molecular pathways of Cd toxicity. T2 - Current Opinion in Toxicology T1 - An overview of molecular mechanisms in cadmium toxicity VL - 19 SP - 56 EP - 62 DO - 10.1016/j.cotox.2019.12.002 ER -
@article{ author = "Đukić-Ćosić, Danijela and Baralić, Katarina and Javorac, Dragana and Buha-Đorđević, Aleksandra and Bulat, Zorica", year = "2020", abstract = "Cadmium (Cd), one of the most important environmental pollutants, can cause a number of toxic effects. These effects are the result of more than one mechanisms of toxicity, all interrelated in their complexity. Thus, it is difficult to identify a fine line between these mechanisms of Cd toxicity, making their understanding highly complicated. The most important mechanisms by which Cd manifests its toxic effects include changes in gene expression and inhibition of damaged DNA repair, interference of apoptosis and autophagy, oxidative stress, and interaction with bioelements. In this review, we will give a brief overview of the recent developments and findings on the most relevant general and specific mechanisms and molecular pathways of Cd toxicity.", journal = "Current Opinion in Toxicology", title = "An overview of molecular mechanisms in cadmium toxicity", volume = "19", pages = "56-62", doi = "10.1016/j.cotox.2019.12.002" }
Đukić-Ćosić, D., Baralić, K., Javorac, D., Buha-Đorđević, A.,& Bulat, Z.. (2020). An overview of molecular mechanisms in cadmium toxicity. in Current Opinion in Toxicology, 19, 56-62. https://doi.org/10.1016/j.cotox.2019.12.002
Đukić-Ćosić D, Baralić K, Javorac D, Buha-Đorđević A, Bulat Z. An overview of molecular mechanisms in cadmium toxicity. in Current Opinion in Toxicology. 2020;19:56-62. doi:10.1016/j.cotox.2019.12.002 .
Đukić-Ćosić, Danijela, Baralić, Katarina, Javorac, Dragana, Buha-Đorđević, Aleksandra, Bulat, Zorica, "An overview of molecular mechanisms in cadmium toxicity" in Current Opinion in Toxicology, 19 (2020):56-62, https://doi.org/10.1016/j.cotox.2019.12.002 . .