An overview of molecular mechanisms in cadmium toxicity
Samo za registrovane korisnike
2020
Autori
Đukić-Ćosić, DanijelaBaralić, Katarina
Javorac, Dragana
Buha-Đorđević, Aleksandra
Bulat, Zorica
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Cadmium (Cd), one of the most important environmental pollutants, can cause a number of toxic effects. These effects are the result of more than one mechanisms of toxicity, all interrelated in their complexity. Thus, it is difficult to identify a fine line between these mechanisms of Cd toxicity, making their understanding highly complicated. The most important mechanisms by which Cd manifests its toxic effects include changes in gene expression and inhibition of damaged DNA repair, interference of apoptosis and autophagy, oxidative stress, and interaction with bioelements. In this review, we will give a brief overview of the recent developments and findings on the most relevant general and specific mechanisms and molecular pathways of Cd toxicity.
Ključne reči:
Apoptosis / Autophagy / Bioelements / Cadmium / Gene relation / Oxidative stressIzvor:
Current Opinion in Toxicology, 2020, 19, 56-62Finansiranje / projekti:
- Unapređenje i razvoj higijenskih i tehnoloških postupaka u proizvodnji namirnica životinjskog porekla u cilju dobijanja kvalitetnih i bezbednih proizvoda konkurentnih na svetskom tržištu (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-46009)
DOI: 10.1016/j.cotox.2019.12.002
ISSN: 2468-2020
WoS: 000531649300011
Scopus: 2-s2.0-85077917808
Institucija/grupa
PharmacyTY - JOUR AU - Đukić-Ćosić, Danijela AU - Baralić, Katarina AU - Javorac, Dragana AU - Buha-Đorđević, Aleksandra AU - Bulat, Zorica PY - 2020 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3511 AB - Cadmium (Cd), one of the most important environmental pollutants, can cause a number of toxic effects. These effects are the result of more than one mechanisms of toxicity, all interrelated in their complexity. Thus, it is difficult to identify a fine line between these mechanisms of Cd toxicity, making their understanding highly complicated. The most important mechanisms by which Cd manifests its toxic effects include changes in gene expression and inhibition of damaged DNA repair, interference of apoptosis and autophagy, oxidative stress, and interaction with bioelements. In this review, we will give a brief overview of the recent developments and findings on the most relevant general and specific mechanisms and molecular pathways of Cd toxicity. T2 - Current Opinion in Toxicology T1 - An overview of molecular mechanisms in cadmium toxicity VL - 19 SP - 56 EP - 62 DO - 10.1016/j.cotox.2019.12.002 ER -
@article{ author = "Đukić-Ćosić, Danijela and Baralić, Katarina and Javorac, Dragana and Buha-Đorđević, Aleksandra and Bulat, Zorica", year = "2020", abstract = "Cadmium (Cd), one of the most important environmental pollutants, can cause a number of toxic effects. These effects are the result of more than one mechanisms of toxicity, all interrelated in their complexity. Thus, it is difficult to identify a fine line between these mechanisms of Cd toxicity, making their understanding highly complicated. The most important mechanisms by which Cd manifests its toxic effects include changes in gene expression and inhibition of damaged DNA repair, interference of apoptosis and autophagy, oxidative stress, and interaction with bioelements. In this review, we will give a brief overview of the recent developments and findings on the most relevant general and specific mechanisms and molecular pathways of Cd toxicity.", journal = "Current Opinion in Toxicology", title = "An overview of molecular mechanisms in cadmium toxicity", volume = "19", pages = "56-62", doi = "10.1016/j.cotox.2019.12.002" }
Đukić-Ćosić, D., Baralić, K., Javorac, D., Buha-Đorđević, A.,& Bulat, Z.. (2020). An overview of molecular mechanisms in cadmium toxicity. in Current Opinion in Toxicology, 19, 56-62. https://doi.org/10.1016/j.cotox.2019.12.002
Đukić-Ćosić D, Baralić K, Javorac D, Buha-Đorđević A, Bulat Z. An overview of molecular mechanisms in cadmium toxicity. in Current Opinion in Toxicology. 2020;19:56-62. doi:10.1016/j.cotox.2019.12.002 .
Đukić-Ćosić, Danijela, Baralić, Katarina, Javorac, Dragana, Buha-Đorđević, Aleksandra, Bulat, Zorica, "An overview of molecular mechanisms in cadmium toxicity" in Current Opinion in Toxicology, 19 (2020):56-62, https://doi.org/10.1016/j.cotox.2019.12.002 . .