Vaccination has been well recognised as a critically important tool in preventing infectious disease, yet incomplete immunisation coverage remains a major obstacle to achieving disease control and eradication. As medical products for global access, vaccines need to be safe, effective and inexpensive. In line with these goals, continuous improvements of vaccine delivery strategies are necessary to achieve the full potential of immunisation. Novel technologies related to vaccine delivery and route of administration, use of advanced adjuvants and controlled antigen release (single-dose immunisation) approaches are expected to contribute to improved coverage and patient compliance. This review discusses the application of micro-and nano-technologies in the alternative routes of vaccine administration (mucosal and cutaneous vaccination), oral vaccine delivery as well as vaccine encapsulation with the aim of controlled antigen release for single-dose vaccination.
TY - JOUR
AU - Lemoine, Céline
AU - Thakur, Aneesh
AU - Krajišnik, Danina
AU - Guyon, Romain
AU - Longet, S.
AU - Razim, Agnieszka
AU - Górska, Sabina
AU - Pantelić, Ivana
AU - Ilić, Tanja
AU - Nikolić, Ines
AU - Lavelle, Ed C.
AU - Gamian, Ed C.
AU - Savić, Snežana
AU - Milicic, Anita
PY - 2020
UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/3627
AB - Vaccination has been well recognised as a critically important tool in preventing infectious disease, yet incomplete immunisation coverage remains a major obstacle to achieving disease control and eradication. As medical products for global access, vaccines need to be safe, effective and inexpensive. In line with these goals, continuous improvements of vaccine delivery strategies are necessary to achieve the full potential of immunisation. Novel technologies related to vaccine delivery and route of administration, use of advanced adjuvants and controlled antigen release (single-dose immunisation) approaches are expected to contribute to improved coverage and patient compliance. This review discusses the application of micro-and nano-technologies in the alternative routes of vaccine administration (mucosal and cutaneous vaccination), oral vaccine delivery as well as vaccine encapsulation with the aim of controlled antigen release for single-dose vaccination.
PB - MDPI AG
T2 - Vaccines
T1 - Technological approaches for improving vaccination compliance and coverage
VL - 8
IS - 2
SP - 1
EP - 28
DO - 10.3390/vaccines8020304
ER -
@article{
author = "Lemoine, Céline and Thakur, Aneesh and Krajišnik, Danina and Guyon, Romain and Longet, S. and Razim, Agnieszka and Górska, Sabina and Pantelić, Ivana and Ilić, Tanja and Nikolić, Ines and Lavelle, Ed C. and Gamian, Ed C. and Savić, Snežana and Milicic, Anita",
year = "2020",
abstract = "Vaccination has been well recognised as a critically important tool in preventing infectious disease, yet incomplete immunisation coverage remains a major obstacle to achieving disease control and eradication. As medical products for global access, vaccines need to be safe, effective and inexpensive. In line with these goals, continuous improvements of vaccine delivery strategies are necessary to achieve the full potential of immunisation. Novel technologies related to vaccine delivery and route of administration, use of advanced adjuvants and controlled antigen release (single-dose immunisation) approaches are expected to contribute to improved coverage and patient compliance. This review discusses the application of micro-and nano-technologies in the alternative routes of vaccine administration (mucosal and cutaneous vaccination), oral vaccine delivery as well as vaccine encapsulation with the aim of controlled antigen release for single-dose vaccination.",
publisher = "MDPI AG",
journal = "Vaccines",
title = "Technological approaches for improving vaccination compliance and coverage",
volume = "8",
number = "2",
pages = "1-28",
doi = "10.3390/vaccines8020304"
}
Lemoine, C., Thakur, A., Krajišnik, D., Guyon, R., Longet, S., Razim, A., Górska, S., Pantelić, I., Ilić, T., Nikolić, I., Lavelle, E. C., Gamian, E. C., Savić, S.,& Milicic, A.. (2020). Technological approaches for improving vaccination compliance and coverage. in Vaccines
MDPI AG., 8(2), 1-28.
https://doi.org/10.3390/vaccines8020304
Lemoine C, Thakur A, Krajišnik D, Guyon R, Longet S, Razim A, Górska S, Pantelić I, Ilić T, Nikolić I, Lavelle EC, Gamian EC, Savić S, Milicic A. Technological approaches for improving vaccination compliance and coverage. in Vaccines. 2020;8(2):1-28.
doi:10.3390/vaccines8020304 .
Lemoine, Céline, Thakur, Aneesh, Krajišnik, Danina, Guyon, Romain, Longet, S., Razim, Agnieszka, Górska, Sabina, Pantelić, Ivana, Ilić, Tanja, Nikolić, Ines, Lavelle, Ed C., Gamian, Ed C., Savić, Snežana, Milicic, Anita, "Technological approaches for improving vaccination compliance and coverage" in Vaccines, 8, no. 2 (2020):1-28,
https://doi.org/10.3390/vaccines8020304 . .
