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Methoxy-substituted hydroxychalcone reduces biofilm production, adhesion, and surface motility of Acinetobacter baumannii by inhibiting ompA gene expression
(FEMS Online Conference on Microbiology, 2020)
Uvod: Acinetobacter baumannii je globalno rasprostranjen nozokomijalni patogen koji se odlikuje izuzetnom sposobnošću ekstremno brzog sticanja rezistencije na antibiotike, kao i adaptacije na preživljavanje u suvim uslovima ...
Nanosuspensions of novel deuterated pyrazoloquinolinones ligand (DK-I-56-1): lyophilization procedure development through cryoprotectant selection and stability study
(2020)
Despite of good pharmacodynamics of DK-I-56-1, novel deuterated pyrazoloquinolinones ligand, low solubility limits its administration. Nanosuspensions can help to overcome this problem, but its small particle size usually ...
Nove protein-ligand interakcije amidnih BET inhibitora otkrivene derivatizacijom (+)-JQ1 molekula
(Konkurs za izbor najboljih naučno-istraživačkih radova studenata doktorskih akademskih studija, 2021)
Histoni su bazni proteini koji interakcijom preko baznih ostataka lizina sa fosfatnim grupama DNK omogućavaju upakivanje DNK molekula i formiranje nukleozoma i hromatina. Jedan od glavnih mehanizama aktivacije hromatina ...
Systematic review and meta-synthesis - challenges and problems during professional development of pharmacy preceptors
(Konkurs za izbor najboljih naučno-istraživačkih radova studenata doktorskih akademskih studija, 2021)
Introduction
The process of transformation of pharmacy is closely related to the professional development of pharmacists, with the aim of increasing their competencies and performance. The biggest changes in this process ...
Design and synthesis of Hsp90 PROTAC degraders as potential anticancer agents
(Konkurs za izbor najboljih naučno-istraživačkih radova studenata doktorskih akademskih studija, 2019)
Hsp90 (Heat Shock Protein 90) is a chaperon protein which plays role in protein folding and maintaining protein structures. It is overexpressed in cancer and stabilizes many oncoproteins and as such represents a good target ...