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Study of vitamin E microencapsulation and controlled release from chitosan/sodium lauryl ether sulfate microcapsules

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2021
Authors
Milinković Budinčić, Jelena
Petrović, Lidija
Đekić, Ljiljana
Fraj, Jadranka
Bučko, Sandra
Katona, Jaroslav
Spasojević, Ljiljana
Article (Published version)
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Abstract
Potential benefit of microencapsulation is its ability to deliver and protect incorporated ingredients such as vitamin E. Microcapsule wall properties can be changed by adding of coss-linking agents that are usually considered toxic for application. The microcapsules were prepared by a spray-drying technique using coacervation method, by depositing the coacervate formed in the mixture of chitosan and sodium lauryl ether sulfate to the oil/water interface. All obtained microcapsules suspensions had slightly lower mean diameter compared to the starting emulsion (6.85 ± 0.213 μm), which shows their good stability during the drying process. The choice and absence of cross-linking agents had influence on kinetics of vitamin E release. Encapsulation efficiency of microcapsules without cross-linking agent was 73.17 ± 0.64 %. This study avoided the use of aldehydes as cross-linking agents and found that chitosan/SLES complex can be used as wall material for the microencapsulation of hydrophobi...c active molecules in cosmetic industry.

Keywords:
Chitosan / Glutaraldehyde / Formaldehyde / Vitamin E / Microencapsulation / Controlled release
Source:
Carbohydrate Polymers, 2021, 251
Publisher:
  • Elsevier Ltd
Projects:
  • Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 451-03-68/2020-14/200134 (University of Novi Sad, Faculty of Technology) (RS-200134)

DOI: 10.1016/j.carbpol.2020.116988

ISSN: 0144-8617

WoS: 000582801500013

Scopus: 2-s2.0-85090219414
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URI
https://farfar.pharmacy.bg.ac.rs/handle/123456789/3774
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  • Radovi istraživača / Researchers’ publications
Institution
Pharmacy

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