Spectrophotometric and potentiometric determination of acidic constants of oxo-phenyl pyridinium monoxime and dioxime
Само за регистроване кориснике
1988
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The UV absorption spectra of 1-(1-hydroxyimino-2-oxo-2-phenyl) pyridinium chloride (compound I) and 1-(1-hydroxyimino-2-oxo-2-phenyl)-4-hydroxyiminomethyl pyridinium chloride (compound II) in water solution at different pH values have been measured. The spectral changes, with changing pH, in aqueous solutions are attributed to the dissociation of individual functional groups of the compounds. The mixed acidic constants (pK′a) of the investigated monoxime and dioxime, have been determined spectrophotometrically in the series of Britton-Robinson's buffer solutions in the pH range 3.0-5.19 and 7.70-9.90 (t=25±0.5°C, I=0.2). The following pK′a values have been obtained for monoxime pK′a1=4.30 and for dioxime pK′a1=4.28, pK′a2=8.36. Thermodynamic acidic constants (pKa) have been determined on the basis of potentiometric titrations and they have been found to be pKa1=4.32 for compound I and pKa1=4.27, pKa2=8.51 for compound II. The values obtained by transferring pK′a into pKa are in good ag...reement with the values obtained potentiometrically.
Кључне речи:
Acidic constants / Potential antidotes / Pyridinium oximesИзвор:
Monatshefte für Chemie Chemical Monthly, 1988, 119, 10, 1069-1078Издавач:
- Springer-Verlag
Институција/група
PharmacyTY - JOUR AU - Milovanović, L.T AU - Karljiković-Rajić, Katarina AU - Stanković, B.S PY - 1988 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/38 AB - The UV absorption spectra of 1-(1-hydroxyimino-2-oxo-2-phenyl) pyridinium chloride (compound I) and 1-(1-hydroxyimino-2-oxo-2-phenyl)-4-hydroxyiminomethyl pyridinium chloride (compound II) in water solution at different pH values have been measured. The spectral changes, with changing pH, in aqueous solutions are attributed to the dissociation of individual functional groups of the compounds. The mixed acidic constants (pK′a) of the investigated monoxime and dioxime, have been determined spectrophotometrically in the series of Britton-Robinson's buffer solutions in the pH range 3.0-5.19 and 7.70-9.90 (t=25±0.5°C, I=0.2). The following pK′a values have been obtained for monoxime pK′a1=4.30 and for dioxime pK′a1=4.28, pK′a2=8.36. Thermodynamic acidic constants (pKa) have been determined on the basis of potentiometric titrations and they have been found to be pKa1=4.32 for compound I and pKa1=4.27, pKa2=8.51 for compound II. The values obtained by transferring pK′a into pKa are in good agreement with the values obtained potentiometrically. PB - Springer-Verlag T2 - Monatshefte für Chemie Chemical Monthly T1 - Spectrophotometric and potentiometric determination of acidic constants of oxo-phenyl pyridinium monoxime and dioxime VL - 119 IS - 10 SP - 1069 EP - 1078 DO - 10.1007/BF00809259 ER -
@article{ author = "Milovanović, L.T and Karljiković-Rajić, Katarina and Stanković, B.S", year = "1988", abstract = "The UV absorption spectra of 1-(1-hydroxyimino-2-oxo-2-phenyl) pyridinium chloride (compound I) and 1-(1-hydroxyimino-2-oxo-2-phenyl)-4-hydroxyiminomethyl pyridinium chloride (compound II) in water solution at different pH values have been measured. The spectral changes, with changing pH, in aqueous solutions are attributed to the dissociation of individual functional groups of the compounds. The mixed acidic constants (pK′a) of the investigated monoxime and dioxime, have been determined spectrophotometrically in the series of Britton-Robinson's buffer solutions in the pH range 3.0-5.19 and 7.70-9.90 (t=25±0.5°C, I=0.2). The following pK′a values have been obtained for monoxime pK′a1=4.30 and for dioxime pK′a1=4.28, pK′a2=8.36. Thermodynamic acidic constants (pKa) have been determined on the basis of potentiometric titrations and they have been found to be pKa1=4.32 for compound I and pKa1=4.27, pKa2=8.51 for compound II. The values obtained by transferring pK′a into pKa are in good agreement with the values obtained potentiometrically.", publisher = "Springer-Verlag", journal = "Monatshefte für Chemie Chemical Monthly", title = "Spectrophotometric and potentiometric determination of acidic constants of oxo-phenyl pyridinium monoxime and dioxime", volume = "119", number = "10", pages = "1069-1078", doi = "10.1007/BF00809259" }
Milovanović, L.T, Karljiković-Rajić, K.,& Stanković, B.S. (1988). Spectrophotometric and potentiometric determination of acidic constants of oxo-phenyl pyridinium monoxime and dioxime. in Monatshefte für Chemie Chemical Monthly Springer-Verlag., 119(10), 1069-1078. https://doi.org/10.1007/BF00809259
Milovanović L, Karljiković-Rajić K, Stanković B. Spectrophotometric and potentiometric determination of acidic constants of oxo-phenyl pyridinium monoxime and dioxime. in Monatshefte für Chemie Chemical Monthly. 1988;119(10):1069-1078. doi:10.1007/BF00809259 .
Milovanović, L.T, Karljiković-Rajić, Katarina, Stanković, B.S, "Spectrophotometric and potentiometric determination of acidic constants of oxo-phenyl pyridinium monoxime and dioxime" in Monatshefte für Chemie Chemical Monthly, 119, no. 10 (1988):1069-1078, https://doi.org/10.1007/BF00809259 . .