Effects of short-term magnesium supplementation on ionized, total magnesium and other relevant electrolytes levels
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2022
Authors
Ivanović, Nevena
Radosavljević, Branimir
Zeković, Milica
Korčok, Davor
Ignjatović, Svetlana

Đorđević, Brižita

Milinković, Neda

Article (Published version)

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This study aimed to investigate the short-term effects of three magnesium (Mg) dietary supplements containing mineral immediately available for absorption on Mg biochemical status indices (ionized and total Mg), as well as their effects on electrolytes levels in healthy female young adults (n = 61). After a 10-days intervention period supplementation with powder/granulate containing Mg oxide led to an increase in both ionized Mg concentration and % in total Mg in comparison with the baseline. Supplementation with Mg citrate was associated with the significant increase in % of ionized fraction and decrease in serum total Mg concentration. By contrast, among participants consuming Mg carbonate in the form of effervescent tablets ionized Mg concentration and % in total Mg decreased, without detectable changes in serum total Mg. In conclusion, after the short-term supplementation period, Mg oxide demonstrated superior bioavailability compared to the other examined Mg supplements without af...fecting other minerals’ levels.
Keywords:
Ionized magnesium / Magnesium / Magnesium carbonate / Magnesium citrate / Magnesium oxide / Mineral status / Pharmaceutical dosage / SupplementsSource:
BioMetals, 2022, 35, 267-283Publisher:
- Springer Nature B.V.
DOI: 10.1007/s10534-022-00363-y
ISSN: 0966-0844
WoS: 000743839200001
Scopus: 2-s2.0-85123104165
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PharmacyTY - JOUR AU - Ivanović, Nevena AU - Radosavljević, Branimir AU - Zeković, Milica AU - Korčok, Davor AU - Ignjatović, Svetlana AU - Đorđević, Brižita AU - Milinković, Neda PY - 2022 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4048 AB - This study aimed to investigate the short-term effects of three magnesium (Mg) dietary supplements containing mineral immediately available for absorption on Mg biochemical status indices (ionized and total Mg), as well as their effects on electrolytes levels in healthy female young adults (n = 61). After a 10-days intervention period supplementation with powder/granulate containing Mg oxide led to an increase in both ionized Mg concentration and % in total Mg in comparison with the baseline. Supplementation with Mg citrate was associated with the significant increase in % of ionized fraction and decrease in serum total Mg concentration. By contrast, among participants consuming Mg carbonate in the form of effervescent tablets ionized Mg concentration and % in total Mg decreased, without detectable changes in serum total Mg. In conclusion, after the short-term supplementation period, Mg oxide demonstrated superior bioavailability compared to the other examined Mg supplements without affecting other minerals’ levels. PB - Springer Nature B.V. T2 - BioMetals T1 - Effects of short-term magnesium supplementation on ionized, total magnesium and other relevant electrolytes levels VL - 35 SP - 267 EP - 283 DO - 10.1007/s10534-022-00363-y ER -
@article{ author = "Ivanović, Nevena and Radosavljević, Branimir and Zeković, Milica and Korčok, Davor and Ignjatović, Svetlana and Đorđević, Brižita and Milinković, Neda", year = "2022", abstract = "This study aimed to investigate the short-term effects of three magnesium (Mg) dietary supplements containing mineral immediately available for absorption on Mg biochemical status indices (ionized and total Mg), as well as their effects on electrolytes levels in healthy female young adults (n = 61). After a 10-days intervention period supplementation with powder/granulate containing Mg oxide led to an increase in both ionized Mg concentration and % in total Mg in comparison with the baseline. Supplementation with Mg citrate was associated with the significant increase in % of ionized fraction and decrease in serum total Mg concentration. By contrast, among participants consuming Mg carbonate in the form of effervescent tablets ionized Mg concentration and % in total Mg decreased, without detectable changes in serum total Mg. In conclusion, after the short-term supplementation period, Mg oxide demonstrated superior bioavailability compared to the other examined Mg supplements without affecting other minerals’ levels.", publisher = "Springer Nature B.V.", journal = "BioMetals", title = "Effects of short-term magnesium supplementation on ionized, total magnesium and other relevant electrolytes levels", volume = "35", pages = "267-283", doi = "10.1007/s10534-022-00363-y" }
Ivanović, N., Radosavljević, B., Zeković, M., Korčok, D., Ignjatović, S., Đorđević, B.,& Milinković, N.. (2022). Effects of short-term magnesium supplementation on ionized, total magnesium and other relevant electrolytes levels. in BioMetals Springer Nature B.V.., 35, 267-283. https://doi.org/10.1007/s10534-022-00363-y
Ivanović N, Radosavljević B, Zeković M, Korčok D, Ignjatović S, Đorđević B, Milinković N. Effects of short-term magnesium supplementation on ionized, total magnesium and other relevant electrolytes levels. in BioMetals. 2022;35:267-283. doi:10.1007/s10534-022-00363-y .
Ivanović, Nevena, Radosavljević, Branimir, Zeković, Milica, Korčok, Davor, Ignjatović, Svetlana, Đorđević, Brižita, Milinković, Neda, "Effects of short-term magnesium supplementation on ionized, total magnesium and other relevant electrolytes levels" in BioMetals, 35 (2022):267-283, https://doi.org/10.1007/s10534-022-00363-y . .
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