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dc.creatorVujić, Zorica
dc.creatorRadulović, D
dc.creatorLucić, B
dc.creatorErić, Slavica
dc.creatorKuntić, Vesna
dc.date.accessioned2019-09-02T10:56:30Z
dc.date.available2019-09-02T10:56:30Z
dc.date.issued2003
dc.identifier.issn0009-5893
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/414
dc.description.abstractMaprotiline, desipramine and moclobemide are widely used in the treatment of depression. The content of these antidepressants in bulk drug and pharmaceutical formulations were determined by TLC and in situ densitometry using a Camag scanner In order to achieve the best condition, mathematical statistical model factorial design was chosen. The partition coefficients, calculated by applying commercial drug design software, were correlated with chromatographic behaviour of these substances. After separation on Silica gel GF(254) using propano-lethanol-ammonium solution (25%) (8:2:0.3 v/v/v) as the mobile phase, the chromatographic zones corresponding to the spots were scanned at 254 nm. Analysing Maprotilin(R) tablets, Pertofran(R) dragees and Auromid(R) film tablets examined the applicability of the method for samples and dosage forms.en
dc.publisherVieweg, Wiesbaden
dc.rightsrestrictedAccess
dc.sourceChromatographia
dc.titleUV-densitometric determination of maprotiline, desipramine and moclobemide in pharmaceutical dosage formsen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractКунтић, Весна; Луцић, Б; Ерић, Славица; Радуловић, Д; Вујић, Зорица;
dc.citation.volume57
dc.citation.issue9-10
dc.citation.spage687
dc.citation.epage689
dc.citation.other57(9-10): 687-689
dc.citation.rankM22
dc.identifier.wos000183320400020
dc.identifier.doi10.1007/BF02491750
dc.identifier.scopus2-s2.0-0037617987
dc.identifier.rcubconv_1399
dc.type.versionpublishedVersion


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