The chromatographic behavior of five myorelaxant drugs has been studied under the conditions used for salting-out thin-layer chromatography (SOTLC) on cellulose and alumina. For this purpose, aqueous ammonium sulfate solutions of different concentration were used as mobile phases. It was established that hR(F) values always decreased in parallel to increasing salt concentrations. When cellulose was used as adsorbent, a linear relationship was observed between the R-M values and the ammonium sulfate content of the mobile phase. Regression data of the plots obtained were used to determine the lipophilicity parameters R-M(0) and C-0. Lipophilicity determined in this way correlated with calculated log P values.
Source:
Journal of Planar Chromatography - Modern TLC, 2003, 16, 2, 144-146
TY - JOUR
AU - Aleksić, Mirjana
AU - Odović, Jadranka
AU - Milojković-Opsenica, Dušanka
AU - Tešić, Živoslav
PY - 2003
UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/415
AB - The chromatographic behavior of five myorelaxant drugs has been studied under the conditions used for salting-out thin-layer chromatography (SOTLC) on cellulose and alumina. For this purpose, aqueous ammonium sulfate solutions of different concentration were used as mobile phases. It was established that hR(F) values always decreased in parallel to increasing salt concentrations. When cellulose was used as adsorbent, a linear relationship was observed between the R-M values and the ammonium sulfate content of the mobile phase. Regression data of the plots obtained were used to determine the lipophilicity parameters R-M(0) and C-0. Lipophilicity determined in this way correlated with calculated log P values.
PB - Research Inst Medicinal Plants, Budakalasz
T2 - Journal of Planar Chromatography - Modern TLC
T1 - Salting-out thin-layer chromatography of several myorelaxants
VL - 16
IS - 2
SP - 144
EP - 146
DO - 10.1556/JPC.16.2003.2.11
ER -
@article{
author = "Aleksić, Mirjana and Odović, Jadranka and Milojković-Opsenica, Dušanka and Tešić, Živoslav",
year = "2003",
abstract = "The chromatographic behavior of five myorelaxant drugs has been studied under the conditions used for salting-out thin-layer chromatography (SOTLC) on cellulose and alumina. For this purpose, aqueous ammonium sulfate solutions of different concentration were used as mobile phases. It was established that hR(F) values always decreased in parallel to increasing salt concentrations. When cellulose was used as adsorbent, a linear relationship was observed between the R-M values and the ammonium sulfate content of the mobile phase. Regression data of the plots obtained were used to determine the lipophilicity parameters R-M(0) and C-0. Lipophilicity determined in this way correlated with calculated log P values.",
publisher = "Research Inst Medicinal Plants, Budakalasz",
journal = "Journal of Planar Chromatography - Modern TLC",
title = "Salting-out thin-layer chromatography of several myorelaxants",
volume = "16",
number = "2",
pages = "144-146",
doi = "10.1556/JPC.16.2003.2.11"
}
Aleksić, M., Odović, J., Milojković-Opsenica, D.,& Tešić, Ž.. (2003). Salting-out thin-layer chromatography of several myorelaxants. in Journal of Planar Chromatography - Modern TLC
Research Inst Medicinal Plants, Budakalasz., 16(2), 144-146.
https://doi.org/10.1556/JPC.16.2003.2.11
Aleksić M, Odović J, Milojković-Opsenica D, Tešić Ž. Salting-out thin-layer chromatography of several myorelaxants. in Journal of Planar Chromatography - Modern TLC. 2003;16(2):144-146.
doi:10.1556/JPC.16.2003.2.11 .
Aleksić, Mirjana, Odović, Jadranka, Milojković-Opsenica, Dušanka, Tešić, Živoslav, "Salting-out thin-layer chromatography of several myorelaxants" in Journal of Planar Chromatography - Modern TLC, 16, no. 2 (2003):144-146,
https://doi.org/10.1556/JPC.16.2003.2.11 . .
