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The role of laboratory biomarkers in diagnostics and management of COVID-19 patients

Uloga laboratorijskih biomarkera u dijagnostici i praćenju pacijenata sa COVID-19

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2022
The_role_of_pub_2022.pdf (302.2Kb)
Authors
Perović-Blagojević, Iva
Bojanin, Dragana
Ristovski-Kornic, Danijela
Marković, Jelena
Aleksić, Predrag
Subošić, Branko
Vekić, Jelena
Kotur-Stevuljević, Jelena
Article (Published version)
Metadata
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Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of a highly transmittable and heterogenic infection of the respiratory tract, characterized by a broad spectrum of clinical manifestations with a different degree of severity. Medical laboratories play an important role in early diagnosis and management of Coronavirus Disease 2019 (COVID-19) patients. Indeed, the results of several laboratory tests are essential for assessing the severity of the disease, selecting appropriate therapeutic procedures and monitoring treatment response. Routine laboratory testing in COVID-19 patients includes biomarkers of acute phase reaction, hematological and biochemical parameters that indicate tissue injury. The aim of this review paper is to describe the role of these biomarkers in the diagnostics and management of adult and pediatric COVID-19 patients.
Novi koronavirus SARS-CoV-2 je uzročnik lako prenosive i veoma heterogene infekcije respiratornog trakta, koju karakteriše širok spektar kliničkih manifestacija, različitog stepena težine. Medicinske laboratorije igraju važnu ulogu u ranoj dijagnostici i praćenju pacijenata sa COVID-19. Rezultati nekoliko laboratorijskih testova su od suštinskog značaja za procenu težine bolesti, odabir odgovarajućih terapijskih procedura i praćenje odgovora na terapiju. Rutinska laboratorijska ispitivanja kod pacijenata sa COVID-19 uključuju biomarkere akutne faze, hematološke i biohemijske parametre koji ukazuju na oštećenje tkiva. Cilj ovog rada je da se prikaže uloga tih biomarkera u dijagnostici i praćenju toka bolesti kod odraslih i pedijatrijskih pacijenata sa COVID-19.
Keywords:
Biomarker / COVID-19 / laboratory / laboratorijska dijagnostika
Source:
Arhiv za farmaciju, 2022, 72, 2, 231-246
Publisher:
  • Beograd : Savez farmaceutskih udruženja Srbije

DOI: 10.5937/arhfarm72-36369

ISSN: 0004-1963

Scopus: 2-s2.0-85135618624
[ Google Scholar ]
URI
https://farfar.pharmacy.bg.ac.rs/handle/123456789/4190
Collections
  • Radovi istraživača / Researchers’ publications
Institution/Community
Pharmacy
TY  - JOUR
AU  - Perović-Blagojević, Iva
AU  - Bojanin, Dragana
AU  - Ristovski-Kornic, Danijela
AU  - Marković, Jelena
AU  - Aleksić, Predrag
AU  - Subošić, Branko
AU  - Vekić, Jelena
AU  - Kotur-Stevuljević, Jelena
PY  - 2022
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/4190
AB  - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of a highly
transmittable and heterogenic infection of the respiratory tract, characterized by a broad spectrum
of clinical manifestations with a different degree of severity. Medical laboratories play an
important role in early diagnosis and management of Coronavirus Disease 2019 (COVID-19)
patients. Indeed, the results of several laboratory tests are essential for assessing the severity of
the disease, selecting appropriate therapeutic procedures and monitoring treatment response.
Routine laboratory testing in COVID-19 patients includes biomarkers of acute phase reaction,
hematological and biochemical parameters that indicate tissue injury. The aim of this review
paper is to describe the role of these biomarkers in the diagnostics and management of adult and
pediatric COVID-19 patients.
AB  - Novi koronavirus SARS-CoV-2 je uzročnik lako prenosive i veoma heterogene infekcije respiratornog trakta, koju karakteriše širok spektar kliničkih manifestacija, različitog stepena težine. Medicinske laboratorije igraju važnu ulogu u ranoj dijagnostici i praćenju pacijenata sa COVID-19. Rezultati nekoliko laboratorijskih testova su od suštinskog značaja za procenu težine bolesti, odabir odgovarajućih terapijskih procedura i praćenje odgovora na terapiju. Rutinska laboratorijska ispitivanja kod pacijenata sa COVID-19 uključuju biomarkere akutne faze, hematološke i biohemijske parametre koji ukazuju na oštećenje tkiva. Cilj ovog rada je da se prikaže uloga tih biomarkera u dijagnostici i praćenju toka bolesti kod odraslih i pedijatrijskih pacijenata sa COVID-19.
PB  - Beograd : Savez farmaceutskih udruženja Srbije
T2  - Arhiv za farmaciju
T1  - The role of laboratory biomarkers in diagnostics and management of COVID-19 patients
T1  - Uloga laboratorijskih biomarkera u dijagnostici i praćenju pacijenata sa COVID-19
VL  - 72
IS  - 2
SP  - 231
EP  - 246
DO  - 10.5937/arhfarm72-36369
ER  - 
@article{
author = "Perović-Blagojević, Iva and Bojanin, Dragana and Ristovski-Kornic, Danijela and Marković, Jelena and Aleksić, Predrag and Subošić, Branko and Vekić, Jelena and Kotur-Stevuljević, Jelena",
year = "2022",
abstract = "Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of a highly
transmittable and heterogenic infection of the respiratory tract, characterized by a broad spectrum
of clinical manifestations with a different degree of severity. Medical laboratories play an
important role in early diagnosis and management of Coronavirus Disease 2019 (COVID-19)
patients. Indeed, the results of several laboratory tests are essential for assessing the severity of
the disease, selecting appropriate therapeutic procedures and monitoring treatment response.
Routine laboratory testing in COVID-19 patients includes biomarkers of acute phase reaction,
hematological and biochemical parameters that indicate tissue injury. The aim of this review
paper is to describe the role of these biomarkers in the diagnostics and management of adult and
pediatric COVID-19 patients., Novi koronavirus SARS-CoV-2 je uzročnik lako prenosive i veoma heterogene infekcije respiratornog trakta, koju karakteriše širok spektar kliničkih manifestacija, različitog stepena težine. Medicinske laboratorije igraju važnu ulogu u ranoj dijagnostici i praćenju pacijenata sa COVID-19. Rezultati nekoliko laboratorijskih testova su od suštinskog značaja za procenu težine bolesti, odabir odgovarajućih terapijskih procedura i praćenje odgovora na terapiju. Rutinska laboratorijska ispitivanja kod pacijenata sa COVID-19 uključuju biomarkere akutne faze, hematološke i biohemijske parametre koji ukazuju na oštećenje tkiva. Cilj ovog rada je da se prikaže uloga tih biomarkera u dijagnostici i praćenju toka bolesti kod odraslih i pedijatrijskih pacijenata sa COVID-19.",
publisher = "Beograd : Savez farmaceutskih udruženja Srbije",
journal = "Arhiv za farmaciju",
title = "The role of laboratory biomarkers in diagnostics and management of COVID-19 patients, Uloga laboratorijskih biomarkera u dijagnostici i praćenju pacijenata sa COVID-19",
volume = "72",
number = "2",
pages = "231-246",
doi = "10.5937/arhfarm72-36369"
}
Perović-Blagojević, I., Bojanin, D., Ristovski-Kornic, D., Marković, J., Aleksić, P., Subošić, B., Vekić, J.,& Kotur-Stevuljević, J.. (2022). The role of laboratory biomarkers in diagnostics and management of COVID-19 patients. in Arhiv za farmaciju
Beograd : Savez farmaceutskih udruženja Srbije., 72(2), 231-246.
https://doi.org/10.5937/arhfarm72-36369
Perović-Blagojević I, Bojanin D, Ristovski-Kornic D, Marković J, Aleksić P, Subošić B, Vekić J, Kotur-Stevuljević J. The role of laboratory biomarkers in diagnostics and management of COVID-19 patients. in Arhiv za farmaciju. 2022;72(2):231-246.
doi:10.5937/arhfarm72-36369 .
Perović-Blagojević, Iva, Bojanin, Dragana, Ristovski-Kornic, Danijela, Marković, Jelena, Aleksić, Predrag, Subošić, Branko, Vekić, Jelena, Kotur-Stevuljević, Jelena, "The role of laboratory biomarkers in diagnostics and management of COVID-19 patients" in Arhiv za farmaciju, 72, no. 2 (2022):231-246,
https://doi.org/10.5937/arhfarm72-36369 . .

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