FarFaR - Pharmacy Repository
University of Belgrade, Faculty of Pharmacy
    • English
    • Српски
    • Српски (Serbia)
  • English 
    • English
    • Serbian (Cyrillic)
    • Serbian (Latin)
  • Login
View Item 
  •   FarFaR
  • Pharmacy
  • Radovi istraživača / Researchers’ publications
  • View Item
  •   FarFaR
  • Pharmacy
  • Radovi istraživača / Researchers’ publications
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Polymer-stabilized emulsion systems: Structural characteristics and physical stability evaluation

Authorized Users Only
2003
Authors
Krajišnik, Danina
Milić, J.
Article (Published version)
Metadata
Show full item record
Abstract
In the course of investigation of the effects of polymeric emulsifier (Simulgel(R)A) on the structural characteristics and physical stability (during storage time) of semisolid o/w emulsion systems with different emulsifier concentrations, dispersed droplets of an internal oil phase (4.5-11.5 mum size) were discovered. The degree of dispersity was increased along with increasing polymeric emulsifier concentration (from 1 to 5% m/m), which was shown by microscopic analysis. Experiments were also carried out using pH, electrical conductivity, and rheological (rotational and oscillatory) measurements. Emulsion samples expressed a mild acid value acceptable for topical preparations during a 6-month period. Electrical conductivity of fresh samples ranged from 0.423 to 2.009 mS/cm and after a 6-month period this slightly increased to 0.663-2.890 mS/cm. All emulsion samples revealed plastic flow behavior in fresh state, with changes in flow pattern during storage time. Viscoelastic properties... defined by the oscillatory rheometry results were in good correlation with parameters of rotational rheometry and degree of internal phase dispersity. High yield stress values (flow tests) and favorable low values of damping factor (oscillatory studies) both indicated good internal structuring and long-term stability of sample containing 3% m/m of polymeric emulsifier.

Source:
Drug Development and Industrial Pharmacy, 2003, 29, 6, 701-711
Publisher:
  • Taylor & Francis Ltd, Abingdon

DOI: 10.1081/DDC-120021319

ISSN: 0363-9045

PubMed: 12889788

WoS: 000184157700010

Scopus: 2-s2.0-17144433507
[ Google Scholar ]
7
6
URI
https://farfar.pharmacy.bg.ac.rs/handle/123456789/420
Collections
  • Radovi istraživača / Researchers’ publications
Institution/Community
Pharmacy
TY  - JOUR
AU  - Krajišnik, Danina
AU  - Milić, J.
PY  - 2003
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/420
AB  - In the course of investigation of the effects of polymeric emulsifier (Simulgel(R)A) on the structural characteristics and physical stability (during storage time) of semisolid o/w emulsion systems with different emulsifier concentrations, dispersed droplets of an internal oil phase (4.5-11.5 mum size) were discovered. The degree of dispersity was increased along with increasing polymeric emulsifier concentration (from 1 to 5% m/m), which was shown by microscopic analysis. Experiments were also carried out using pH, electrical conductivity, and rheological (rotational and oscillatory) measurements. Emulsion samples expressed a mild acid value acceptable for topical preparations during a 6-month period. Electrical conductivity of fresh samples ranged from 0.423 to 2.009 mS/cm and after a 6-month period this slightly increased to 0.663-2.890 mS/cm. All emulsion samples revealed plastic flow behavior in fresh state, with changes in flow pattern during storage time. Viscoelastic properties defined by the oscillatory rheometry results were in good correlation with parameters of rotational rheometry and degree of internal phase dispersity. High yield stress values (flow tests) and favorable low values of damping factor (oscillatory studies) both indicated good internal structuring and long-term stability of sample containing 3% m/m of polymeric emulsifier.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Drug Development and Industrial Pharmacy
T1  - Polymer-stabilized emulsion systems: Structural characteristics and physical stability evaluation
VL  - 29
IS  - 6
SP  - 701
EP  - 711
DO  - 10.1081/DDC-120021319
ER  - 
@article{
author = "Krajišnik, Danina and Milić, J.",
year = "2003",
abstract = "In the course of investigation of the effects of polymeric emulsifier (Simulgel(R)A) on the structural characteristics and physical stability (during storage time) of semisolid o/w emulsion systems with different emulsifier concentrations, dispersed droplets of an internal oil phase (4.5-11.5 mum size) were discovered. The degree of dispersity was increased along with increasing polymeric emulsifier concentration (from 1 to 5% m/m), which was shown by microscopic analysis. Experiments were also carried out using pH, electrical conductivity, and rheological (rotational and oscillatory) measurements. Emulsion samples expressed a mild acid value acceptable for topical preparations during a 6-month period. Electrical conductivity of fresh samples ranged from 0.423 to 2.009 mS/cm and after a 6-month period this slightly increased to 0.663-2.890 mS/cm. All emulsion samples revealed plastic flow behavior in fresh state, with changes in flow pattern during storage time. Viscoelastic properties defined by the oscillatory rheometry results were in good correlation with parameters of rotational rheometry and degree of internal phase dispersity. High yield stress values (flow tests) and favorable low values of damping factor (oscillatory studies) both indicated good internal structuring and long-term stability of sample containing 3% m/m of polymeric emulsifier.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Drug Development and Industrial Pharmacy",
title = "Polymer-stabilized emulsion systems: Structural characteristics and physical stability evaluation",
volume = "29",
number = "6",
pages = "701-711",
doi = "10.1081/DDC-120021319"
}
Krajišnik, D.,& Milić, J.. (2003). Polymer-stabilized emulsion systems: Structural characteristics and physical stability evaluation. in Drug Development and Industrial Pharmacy
Taylor & Francis Ltd, Abingdon., 29(6), 701-711.
https://doi.org/10.1081/DDC-120021319
Krajišnik D, Milić J. Polymer-stabilized emulsion systems: Structural characteristics and physical stability evaluation. in Drug Development and Industrial Pharmacy. 2003;29(6):701-711.
doi:10.1081/DDC-120021319 .
Krajišnik, Danina, Milić, J., "Polymer-stabilized emulsion systems: Structural characteristics and physical stability evaluation" in Drug Development and Industrial Pharmacy, 29, no. 6 (2003):701-711,
https://doi.org/10.1081/DDC-120021319 . .

DSpace software copyright © 2002-2015  DuraSpace
About FarFaR - Pharmacy Repository | Send Feedback

OpenAIRERCUB
 

 

All of DSpaceCommunitiesAuthorsTitlesSubjectsThis institutionAuthorsTitlesSubjects

Statistics

View Usage Statistics

DSpace software copyright © 2002-2015  DuraSpace
About FarFaR - Pharmacy Repository | Send Feedback

OpenAIRERCUB