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Study of the lipophilicity and retention behavior of some beta-adrenoceptor antagonists
| dc.creator | Perišić-Janjić, Nada U. | |
| dc.creator | Lučić, Branka | |
| dc.creator | Janjić, Nataša J. | |
| dc.creator | Agbaba, Danica | |
| dc.date.accessioned | 2019-09-02T10:56:45Z | |
| dc.date.available | 2019-09-02T10:56:45Z | |
| dc.date.issued | 2003 | |
| dc.identifier.issn | 0933-4173 | |
| dc.identifier.uri | https://farfar.pharmacy.bg.ac.rs/handle/123456789/424 | |
| dc.description.abstract | The chromatographic behavior of some beta-adrenoceptor antagonists has been studied by RP HPTLC on C-18 with water-acetonitrile (phi = 0.2-0.7) and water-dioxane (phi = 0.1-0.5) mobile phases. The retention mechanism was investigated and retention constants, R-M(0) were determined by extrapolation. Good correlation was obtained between R-M(0) and the slope, m, of chromatographic equations. These retention constants correlated well with log P of beta-adrenoceptor antagonists and can be used as a measure of the lipophilicity of the compounds investigated. | en |
| dc.publisher | Springer Nature | |
| dc.relation | Project “Molecular Structures, Chemical Transformations, Physicochemical Characterization, Pharmaceutical Purity, and Analysis of Pharmacologically Active Compounds, No. 1458)” which is partly financial supported by the Serbian Ministry of Science and Technology. | |
| dc.rights | restrictedAccess | |
| dc.source | Journal of Planar Chromatography - Modern TLC | |
| dc.subject | beta-adrenoceptor antagonists | en |
| dc.subject | R-M(0) | en |
| dc.subject | log P | en |
| dc.title | Study of the lipophilicity and retention behavior of some beta-adrenoceptor antagonists | en |
| dc.type | article | |
| dc.rights.license | ARR | |
| dcterms.abstract | Перишић-Јањић, НУ; Aгбаба, Даница; Луцић, Б; Јањић, НЈ; | |
| dc.citation.volume | 16 | |
| dc.citation.issue | 5 | |
| dc.citation.spage | 347 | |
| dc.citation.epage | 350 | |
| dc.citation.other | 16(5): 347-350 | |
| dc.citation.rank | M23 | |
| dc.identifier.wos | 000187571700003 | |
| dc.identifier.doi | 10.1556/JPC.16.2003.5.3 | |
| dc.identifier.scopus | 2-s2.0-17944399854 | |
| dc.type.version | publishedVersion |
