The concentration stability constants of Fe(III)-orciprenaline complex and Fe(III)-phenylephrine complex were calculated for three different ionic strengths, by modificated Bjerrum's method. The values of thermodynamic stability constants are determined from curve log β = f (I1/2), as interception at ordinate. From the determined thermodynamic stability constants logβ10 =8,28 and logβ02 = 16,24 of the complexes investigated, the values of the ∆G10= - 46,87 kJ/mol and, AG° = -92,76 kJ/mol were calculated for Fe(III)-orciprenaline and Fe(III)- phenylephrine complexes respectively.
Za komplekse Fe(III)-fenilefrin i Fe(III)-orciprenalin određene su vrednosti koncentracionih konstanti stabilnosti na tri jonske jačine (0,024; 0,050 0,075 mol/dm3). Na osnovu ovih vrednosti izračunate su termodinamičke konstante stabilnosti ovih kompleksa ekstrapolacijom dijagrama logβn=f(I) na vrednost I=0. Dobijena vrednost za kompleks Fe(III)-fenilefrin je logβ0 2 = 16,24, a za kompleks Fe(III)-orciprenalin ona iznosi logβ10= 8,28. Izračunate su promene standardne Gibbsove energije za reakciju stvaranja kompleksa: ∆G1°= -46,87 kJ/mol za Fe(III)- orciprenalin i ∆G°2 = -92,76 kJ/mol za Fe(III)-fenilefrin.
Keywords:
complex / Fe(III)- ion / phenylephrine / orciprenaline / thermodynamic stability constant / kompleks / Fe(III) jon / fenilefrin / orciprenalin / termodinamička konstanta stabilnosti
TY - JOUR
AU - Pavun, Leposava
AU - Malešev, Dušan
AU - Veselinović, Dragan S.
PY - 2003
UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/449
AB - The concentration stability constants of Fe(III)-orciprenaline complex and Fe(III)-phenylephrine complex were calculated for three different ionic strengths, by modificated Bjerrum's method. The values of thermodynamic stability constants are determined from curve log β = f (I1/2), as interception at ordinate. From the determined thermodynamic stability constants logβ10 =8,28 and logβ02 = 16,24 of the complexes investigated, the values of the ∆G10= - 46,87 kJ/mol and, AG° = -92,76 kJ/mol were calculated for Fe(III)-orciprenaline and Fe(III)- phenylephrine complexes respectively.
AB - Za komplekse Fe(III)-fenilefrin i Fe(III)-orciprenalin određene su vrednosti koncentracionih konstanti stabilnosti na tri jonske jačine (0,024; 0,050 0,075 mol/dm3). Na osnovu ovih vrednosti izračunate su termodinamičke konstante stabilnosti ovih kompleksa ekstrapolacijom dijagrama logβn=f(I) na vrednost I=0. Dobijena vrednost za kompleks Fe(III)-fenilefrin je logβ0 2 = 16,24, a za kompleks Fe(III)-orciprenalin ona iznosi logβ10= 8,28. Izračunate su promene standardne Gibbsove energije za reakciju stvaranja kompleksa: ∆G1°= -46,87 kJ/mol za Fe(III)- orciprenalin i ∆G°2 = -92,76 kJ/mol za Fe(III)-fenilefrin.
PB - Savez farmaceutskih udruženja Srbije, Beograd
T2 - Arhiv za farmaciju
T1 - Thermodynamic stability constants of complexes of Fe(III)-ion with orciprenaline and phenylephrine
T1 - Termodinamičke konstante stabilnosti kompleksa Fe(III)-jona sa orciprenalinom i fenilefrinom
VL - 53
IS - 1-2
SP - 27
EP - 36
UR - https://hdl.handle.net/21.15107/rcub_farfar_449
ER -
@article{
author = "Pavun, Leposava and Malešev, Dušan and Veselinović, Dragan S.",
year = "2003",
abstract = "The concentration stability constants of Fe(III)-orciprenaline complex and Fe(III)-phenylephrine complex were calculated for three different ionic strengths, by modificated Bjerrum's method. The values of thermodynamic stability constants are determined from curve log β = f (I1/2), as interception at ordinate. From the determined thermodynamic stability constants logβ10 =8,28 and logβ02 = 16,24 of the complexes investigated, the values of the ∆G10= - 46,87 kJ/mol and, AG° = -92,76 kJ/mol were calculated for Fe(III)-orciprenaline and Fe(III)- phenylephrine complexes respectively., Za komplekse Fe(III)-fenilefrin i Fe(III)-orciprenalin određene su vrednosti koncentracionih konstanti stabilnosti na tri jonske jačine (0,024; 0,050 0,075 mol/dm3). Na osnovu ovih vrednosti izračunate su termodinamičke konstante stabilnosti ovih kompleksa ekstrapolacijom dijagrama logβn=f(I) na vrednost I=0. Dobijena vrednost za kompleks Fe(III)-fenilefrin je logβ0 2 = 16,24, a za kompleks Fe(III)-orciprenalin ona iznosi logβ10= 8,28. Izračunate su promene standardne Gibbsove energije za reakciju stvaranja kompleksa: ∆G1°= -46,87 kJ/mol za Fe(III)- orciprenalin i ∆G°2 = -92,76 kJ/mol za Fe(III)-fenilefrin.",
publisher = "Savez farmaceutskih udruženja Srbije, Beograd",
journal = "Arhiv za farmaciju",
title = "Thermodynamic stability constants of complexes of Fe(III)-ion with orciprenaline and phenylephrine, Termodinamičke konstante stabilnosti kompleksa Fe(III)-jona sa orciprenalinom i fenilefrinom",
volume = "53",
number = "1-2",
pages = "27-36",
url = "https://hdl.handle.net/21.15107/rcub_farfar_449"
}
Pavun, L., Malešev, D.,& Veselinović, D. S.. (2003). Thermodynamic stability constants of complexes of Fe(III)-ion with orciprenaline and phenylephrine. in Arhiv za farmaciju
Savez farmaceutskih udruženja Srbije, Beograd., 53(1-2), 27-36.
https://hdl.handle.net/21.15107/rcub_farfar_449
Pavun L, Malešev D, Veselinović DS. Thermodynamic stability constants of complexes of Fe(III)-ion with orciprenaline and phenylephrine. in Arhiv za farmaciju. 2003;53(1-2):27-36.
https://hdl.handle.net/21.15107/rcub_farfar_449 .
Pavun, Leposava, Malešev, Dušan, Veselinović, Dragan S., "Thermodynamic stability constants of complexes of Fe(III)-ion with orciprenaline and phenylephrine" in Arhiv za farmaciju, 53, no. 1-2 (2003):27-36,
https://hdl.handle.net/21.15107/rcub_farfar_449 .
