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Heracleum ternatum from Mt. Durmitor: furanocoumarins, polyphenols and antioxidant activity of leaf and flower extracts
dc.creator | Ušjak, Ljuboš | |
dc.creator | Drobac, Milica | |
dc.creator | Niketić, Marjan | |
dc.creator | Petrović, Silvana | |
dc.date.accessioned | 2023-03-13T15:44:53Z | |
dc.date.available | 2023-03-13T15:44:53Z | |
dc.date.issued | 2022 | |
dc.identifier.isbn | 978-86-6275-140-9 | |
dc.identifier.uri | https://farfar.pharmacy.bg.ac.rs/handle/123456789/4503 | |
dc.description.abstract | In this work, composition and antioxidant activity of dry dichloromethane and methanol extracts of Heracleum ternatum Velen. (Apiaceae) leaves and flowers from Mt Durmitor (Montenegro) were investigated. Using LC-MS, five furanocoumarins were identified in leaf dichloromethane extract (accounting for 23.00 mg/g of dry extract) and eight in flower dichloromethane extract (60.47 mg/g). Dominant in leaf extract was heraclenin (11.64 mg/g), followed by imperatorin (5.90 mg/g), and in flower extract heraclenol (17.55 mg/g), followed by heraclenin (15.04 mg/g). LC-MS analysis revealed eight flavonol glycosides in leaf methanol extract (accounting for 16.18 mg/g of dry extract) and 11 in flower methanol extract (65.82 mg/g), as well as chlorogenic acid in both extracts (4.72 mg/g and trace, respectively). Among detected flavonoids, dominant was quercetin 7-O-rhamnosyl 3-O-glucoside (vincetoxicoside A; 7.95 and 16.77 mg/g), followed by biosides and triosides of kaempferol and methylquercetin. Content of total polyphenols, determined spectrophotometrically using Folin-Ciocalteu reagent, was 87.29 and 98.12 mg of gallic acid equivalents/g of dry methanol extracts. Among methanol extracts, polyphenol richer flower extract showed higher, spectrophotometrically determined, total antioxidant and anti-DPPH activities compared to leaf extract (FRAP=0.80 and 0.65 mmol Fe2+/g; DPPH SC50=83.12 and 90.95 μg/mL). Dichloromethane extracts showed lower anti-DPPH activity (SC50=860.58 and 515.76 μg/mL). | sr |
dc.language.iso | en | sr |
dc.publisher | Department of Biology and Ecology, Faculty of Sciences and Mathematics, University of Niš | sr |
dc.publisher | Institute for Nature Conservation of Serbia, Belgrade | sr |
dc.relation | info:eu-repo/grantAgreement/MESTD/inst-2020/200161/RS// | sr |
dc.rights | openAccess | sr |
dc.rights.uri | https://creativecommons.org/licenses/by-sa/4.0/ | |
dc.source | 14th Symposium on the Flora of Southeastern Serbia and Neighboring Regions - Book of Abstracts | sr |
dc.title | Heracleum ternatum from Mt. Durmitor: furanocoumarins, polyphenols and antioxidant activity of leaf and flower extracts | sr |
dc.type | conferenceObject | sr |
dc.rights.license | BY-SA | sr |
dc.citation.spage | 143 | |
dc.citation.epage | 143 | |
dc.description.other | 14th Symposium on the Flora of Southeastern Serbia and Neighboring Regions, Kladovo, 26th to 29th June 2022 | sr |
dc.identifier.fulltext | http://farfar.pharmacy.bg.ac.rs/bitstream/id/12119/bitstream_12119.pdf | |
dc.identifier.rcub | https://hdl.handle.net/21.15107/rcub_farfar_4503 | |
dc.type.version | publishedVersion | sr |