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dc.creatorRauski, Aleksandra
dc.creatorKosec, Duško
dc.creatorVidić-Danković, Biljana
dc.creatorPlećaš-Solarović, Bosiljka
dc.creatorLeposavić, Gordana
dc.date.accessioned2019-09-02T10:57:48Z
dc.date.available2019-09-02T10:57:48Z
dc.date.issued2003
dc.identifier.issn0020-7454
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/466
dc.description.abstractThe study revealed that β-adrenoceptor blockade with propranolol (0. 40 mg/l00 g/day, s.c.) in adult male DA rats: (i) increased the thymocyte proliferation and apoptosis, (ii) caused disturbances in kinetics of T cell differentiation leading to distinguishable changes in relative proportion of thymocytes at distinct maturational steps and to an expansion of the most mature single positive (CD4+, CD8+) thymocyte pool, (iii) affected the relative proportion of neither CD4+ nor CD8+ peripheral blood lymphocytes (PBL), and (iv) augmented the relative number of CD8+CD25+ cells. Thus, the results suggest the role of β-adrenoceptors) in fine-tuning of T cell maturation, and, possibly, distribution and activation of distinct PBL subsets.en
dc.publisherTaylor and Francis Ltd.
dc.rightsrestrictedAccess
dc.sourceInternational Journal of Neuroscience
dc.subjectPeripheral T-cell phenotypeen
dc.subjectThymocyte apoptosisen
dc.subjectThymocyte differentiationen
dc.subjectThymocyte proliferationen
dc.subjectβ-adrenoceptor blockadeen
dc.titleEffects of beta-adrenoceptor blockade on the phenotypic characteristics of thymocytes and peripheral blood lymphocytesen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractРауски, Aлександра; Косец, Душко; Видић-Данковић, Биљана; Плећаш-Соларовић, Босиљка; Лепосавић, Гордана;
dc.citation.volume113
dc.citation.issue12
dc.citation.spage1653
dc.citation.epage1673
dc.citation.other113(12): 1653-1673
dc.citation.rankM23
dc.identifier.wos000186897000002
dc.identifier.doi10.1080/00207450390245216
dc.identifier.scopus2-s2.0-10744222299
dc.identifier.rcubconv_5236
dc.type.versionpublishedVersion


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