Comparison of HPTLC and HPLC for determination of econazole nitrate in topical dosage forms
Само за регистроване кориснике
2004
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
HPTLC and HPLC methods have been established for separation and quantitative determination of econazole nitrate. HPTLC was performed on silica gel plates with n-butyl acetate-carbon tetrachloride-methanol-diethylamine, 3 + 6 + 2.5 + 0.5 (v/v), as mobile phase. Chromatographic zones, or spots, of econazole base and nitrate were used to quantify econazole nitrate. HPLC was performed on amino and C-8 columns with acetonitrile-water, 30 + 70 (v/v), pH 2.5 (adjusted with phosphoric acid), as a mobile phase. The chromatograms were characterized by single peaks of econazole (amino column) or nitrate (C-8 column). The methods were successfully used for determination of econazole nitrate in spray solution and vaginal pessaries.
Кључне речи:
econazole nitrate / HPTLC / HPLC / pharmaceutical formulationsИзвор:
Journal of Planar Chromatography - Modern TLC, 2004, 17, 2, 109-112Издавач:
- Research Inst Medicinal Plants, Budakalasz
DOI: 10.1556/JPC.17.2004.2.5
ISSN: 0933-4173
WoS: 000221981300005
Scopus: 2-s2.0-2942558545
Институција/група
PharmacyTY - JOUR AU - Popović, Gordana AU - Čakar, Mira AU - Vučićević, Katarina AU - Vladimirov, S AU - Agbaba, Danica PY - 2004 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/479 AB - HPTLC and HPLC methods have been established for separation and quantitative determination of econazole nitrate. HPTLC was performed on silica gel plates with n-butyl acetate-carbon tetrachloride-methanol-diethylamine, 3 + 6 + 2.5 + 0.5 (v/v), as mobile phase. Chromatographic zones, or spots, of econazole base and nitrate were used to quantify econazole nitrate. HPLC was performed on amino and C-8 columns with acetonitrile-water, 30 + 70 (v/v), pH 2.5 (adjusted with phosphoric acid), as a mobile phase. The chromatograms were characterized by single peaks of econazole (amino column) or nitrate (C-8 column). The methods were successfully used for determination of econazole nitrate in spray solution and vaginal pessaries. PB - Research Inst Medicinal Plants, Budakalasz T2 - Journal of Planar Chromatography - Modern TLC T1 - Comparison of HPTLC and HPLC for determination of econazole nitrate in topical dosage forms VL - 17 IS - 2 SP - 109 EP - 112 DO - 10.1556/JPC.17.2004.2.5 ER -
@article{ author = "Popović, Gordana and Čakar, Mira and Vučićević, Katarina and Vladimirov, S and Agbaba, Danica", year = "2004", abstract = "HPTLC and HPLC methods have been established for separation and quantitative determination of econazole nitrate. HPTLC was performed on silica gel plates with n-butyl acetate-carbon tetrachloride-methanol-diethylamine, 3 + 6 + 2.5 + 0.5 (v/v), as mobile phase. Chromatographic zones, or spots, of econazole base and nitrate were used to quantify econazole nitrate. HPLC was performed on amino and C-8 columns with acetonitrile-water, 30 + 70 (v/v), pH 2.5 (adjusted with phosphoric acid), as a mobile phase. The chromatograms were characterized by single peaks of econazole (amino column) or nitrate (C-8 column). The methods were successfully used for determination of econazole nitrate in spray solution and vaginal pessaries.", publisher = "Research Inst Medicinal Plants, Budakalasz", journal = "Journal of Planar Chromatography - Modern TLC", title = "Comparison of HPTLC and HPLC for determination of econazole nitrate in topical dosage forms", volume = "17", number = "2", pages = "109-112", doi = "10.1556/JPC.17.2004.2.5" }
Popović, G., Čakar, M., Vučićević, K., Vladimirov, S.,& Agbaba, D.. (2004). Comparison of HPTLC and HPLC for determination of econazole nitrate in topical dosage forms. in Journal of Planar Chromatography - Modern TLC Research Inst Medicinal Plants, Budakalasz., 17(2), 109-112. https://doi.org/10.1556/JPC.17.2004.2.5
Popović G, Čakar M, Vučićević K, Vladimirov S, Agbaba D. Comparison of HPTLC and HPLC for determination of econazole nitrate in topical dosage forms. in Journal of Planar Chromatography - Modern TLC. 2004;17(2):109-112. doi:10.1556/JPC.17.2004.2.5 .
Popović, Gordana, Čakar, Mira, Vučićević, Katarina, Vladimirov, S, Agbaba, Danica, "Comparison of HPTLC and HPLC for determination of econazole nitrate in topical dosage forms" in Journal of Planar Chromatography - Modern TLC, 17, no. 2 (2004):109-112, https://doi.org/10.1556/JPC.17.2004.2.5 . .