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Linear solvation energy relationship study of selected imidazoline receptor ligands on α1-acid glycoprotein column
| dc.creator | Filipić, Slavica | |
| dc.creator | Ružić, Dušan | |
| dc.creator | Vučićević, Jelica | |
| dc.creator | Nikolić, Katarina | |
| dc.creator | Agbaba, Danica | |
| dc.date.accessioned | 2023-07-18T08:21:05Z | |
| dc.date.available | 2023-07-18T08:21:05Z | |
| dc.date.issued | 2016 | |
| dc.identifier.isbn | 978-86-82475-34-7 | |
| dc.identifier.uri | https://farfar.pharmacy.bg.ac.rs/handle/123456789/4914 | |
| dc.description.abstract | The retention properties of 22 selected imidazoline receptor ligands were studied by high-performance liquid chromatography on α1-acid glycoprotein (AGP) column using 2-propanol as organic additive and Sørensen phosphate buffer (pH 7.0). Linear solvation energy relationships (LSER) were built using isocratic retention factors - log k5, log k8, log k10, log k12, log k15 obtained for (5, 8, 10, 12, 15)% of 2- propanol in mobile phase, respectively and extrapolated log Kw values as dependant variables. Independent variables (Abraham descriptors) for LSER analysis were calculated by ACD/i-Lab software. LSER analysis indicated on McGowan volume, hydrogen bond basicity and excess molar refraction as the most important parameters for all isocratic retention factors and log Kw values of 22 selected imidazoline receptor ligands. | sr |
| dc.language.iso | en | sr |
| dc.publisher | Society of Physical Chemists of Serbia | |
| dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172033/RS// | sr |
| dc.rights | openAccess | sr |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
| dc.source | PHYSICAL CHEMISTRY 2016 (Proceedings) 13th International Conference on Fundamental and Applied Aspects of Physical Chemistry, September 26-30, 2016, Belgrade, Serbia | sr |
| dc.title | Linear solvation energy relationship study of selected imidazoline receptor ligands on α1-acid glycoprotein column | sr |
| dc.type | conferenceObject | sr |
| dc.rights.license | ARR | sr |
| dc.citation.volume | II | |
| dc.citation.spage | 821 | |
| dc.citation.epage | 824 | |
| dc.description.other | 13th International Conference on Fundamental and Applied Aspects of Physical Chemistry, September 26-30, 2016, Belgrade, Serbia | |
| dc.identifier.fulltext | http://farfar.pharmacy.bg.ac.rs/bitstream/id/13496/Linear_solvation_energy_pub_2016.pdf | |
| dc.identifier.rcub | https://hdl.handle.net/21.15107/rcub_farfar_4914 | |
| dc.type.version | publishedVersion | sr |
