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Lekoviti preparati lakasativa i antidijaroika - farmaceutsko tehnološki aspekt

dc.creatorĐurić, Zorica
dc.creatorJovanović, Milica
dc.creatorParojčić, Jelena
dc.creatorIbrić, Svetlana
dc.date.accessioned2019-09-02T10:58:23Z
dc.date.available2019-09-02T10:58:23Z
dc.date.issued2004
dc.identifier.issn0004-1963
dc.identifier.urihttps://farfar.pharmacy.bg.ac.rs/handle/123456789/491
dc.description.abstractIn this report preparations of laxatives and antidiarrhoeals and the technological procedures used in production, have been reviewed.The importance of special technological procedure as freeze drying in the production and stabilisation has been explained. The most frequent dosage forms for these drugs are tablets.Good physical characteristics of tablets, insignificant variation of drug content, uniformity of dosage as required bioavailability are to bi provided by using adequate combination of excipients in the formulation and by proper selection of production method and order of technological operations.Additional requirements are to be achieved in the production of chewable tablets , frequently used as a dosage form for laxatives as calcium polycarbophil. Basic concept of tablet production validation is included in this report.en
dc.description.abstractU radu su prikazani lekoviti preparati laksativa i antidijaroika i metode koje se koriste u proizvodnji. Objašnjen je značaj specijalnih tehnoloških postupaka kao što je liofilizacija u proizvodnji i stabilizaciji nekih proizvoda iz ove grupe.Najčešće primenjivani oblik ovih lekovitih supstanci su tablete. Za proizvodnju tableta koje će imati dobre fizičke karakteristike, zanemarljivo mala odstupanja u sadržaju leka, jednolikost doze kao i potrebnu bioraspoloživost, koristi se adekvatna kombinacija pomoćnih materija u formulaciji i pravilan izbor metode izrade. Dodatni zahtevi se postavljaju u slučaju proizvodnje tableta za žvakanje, kao što su tablete sa kalcijum polikarbofilom. U radu su dati i osnovni principi validacije procesa proizvodnje tableta.sr
dc.publisherSavez farmaceutskih udruženja Srbije, Beograd
dc.rightsopenAccess
dc.rights.urihttps://creativecommons.org/licenses/by-sa/4.0/
dc.sourceArhiv za farmaciju
dc.subjectlaxativesen
dc.subjectantidiarrhoealsen
dc.subjectfreeze dryingen
dc.subjecttablet production validationen
dc.subjectlaksativisr
dc.subjectantidijaroicisr
dc.subjectsušenje smrzavanjemsr
dc.subjectvalidacija proizvodnje tabletasr
dc.titlePreparations of laxatives and antidiarrhoeals: Pharmaceutically - technological aspecten
dc.titleLekoviti preparati lakasativa i antidijaroika - farmaceutsko tehnološki aspektsr
dc.typearticle
dc.rights.licenseBY-SA
dcterms.abstractЈовановић, Милица; Ђурић, Зорица; Ибрић, Светлана; Паројчић, Јелена; Лековити препарати лакасатива и антидијароика - фармацеутско технолошки аспект; Лековити препарати лакасатива и антидијароика - фармацеутско технолошки аспект;
dc.citation.volume54
dc.citation.issue3
dc.citation.spage315
dc.citation.epage332
dc.citation.other54(3): 315-332
dc.identifier.fulltexthttps://farfar.pharmacy.bg.ac.rs//bitstream/id/2012/489.pdf
dc.identifier.rcubhttps://hdl.handle.net/21.15107/rcub_farfar_491
dc.type.versionpublishedVersion


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