Computer aided drug design – a step closer to selective HDAC-6 inhibitor?
Abstract
Histone deacetylases (HDACs) are epigenetic erasers, which are considered as transcriptional repressors and potent anticancer targets. Today, 18 human HDACs are identified and divided in four classes. FDA has approved four Histone Deacetylase Inhibitors (HDACi), defined as pan-HDAC inhibitors...
Source:
3rd Freiburg Epigenetic Spring Meeting and COST Action EpiChemBio CM1406, Freiburg, April 10-13, 2016Publisher:
- Freiburg Institute for Advanced Studies
Funding / projects:
- Synthesis, Quantitative Structure and Activity Relationship, Physico-Chemical Characterisation and Analysis of Pharmacologically Active Substances (RS-172033)
- COST CM1406 action
Note:
- Poster
Collections
Institution/Community
PharmacyTY - CONF AU - Ružić, Dušan AU - Nikolić, Katarina AU - Agbaba, Danica AU - Ganesan, A. PY - 2016 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5028 AB - Histone deacetylases (HDACs) are epigenetic erasers, which are considered as transcriptional repressors and potent anticancer targets. Today, 18 human HDACs are identified and divided in four classes. FDA has approved four Histone Deacetylase Inhibitors (HDACi), defined as pan-HDAC inhibitors... PB - Freiburg Institute for Advanced Studies C3 - 3rd Freiburg Epigenetic Spring Meeting and COST Action EpiChemBio CM1406, Freiburg, April 10-13 T1 - Computer aided drug design – a step closer to selective HDAC-6 inhibitor? UR - https://hdl.handle.net/21.15107/rcub_farfar_5028 ER -
@conference{ author = "Ružić, Dušan and Nikolić, Katarina and Agbaba, Danica and Ganesan, A.", year = "2016", abstract = "Histone deacetylases (HDACs) are epigenetic erasers, which are considered as transcriptional repressors and potent anticancer targets. Today, 18 human HDACs are identified and divided in four classes. FDA has approved four Histone Deacetylase Inhibitors (HDACi), defined as pan-HDAC inhibitors...", publisher = "Freiburg Institute for Advanced Studies", journal = "3rd Freiburg Epigenetic Spring Meeting and COST Action EpiChemBio CM1406, Freiburg, April 10-13", title = "Computer aided drug design – a step closer to selective HDAC-6 inhibitor?", url = "https://hdl.handle.net/21.15107/rcub_farfar_5028" }
Ružić, D., Nikolić, K., Agbaba, D.,& Ganesan, A.. (2016). Computer aided drug design – a step closer to selective HDAC-6 inhibitor?. in 3rd Freiburg Epigenetic Spring Meeting and COST Action EpiChemBio CM1406, Freiburg, April 10-13 Freiburg Institute for Advanced Studies.. https://hdl.handle.net/21.15107/rcub_farfar_5028
Ružić D, Nikolić K, Agbaba D, Ganesan A. Computer aided drug design – a step closer to selective HDAC-6 inhibitor?. in 3rd Freiburg Epigenetic Spring Meeting and COST Action EpiChemBio CM1406, Freiburg, April 10-13. 2016;. https://hdl.handle.net/21.15107/rcub_farfar_5028 .
Ružić, Dušan, Nikolić, Katarina, Agbaba, Danica, Ganesan, A., "Computer aided drug design – a step closer to selective HDAC-6 inhibitor?" in 3rd Freiburg Epigenetic Spring Meeting and COST Action EpiChemBio CM1406, Freiburg, April 10-13 (2016), https://hdl.handle.net/21.15107/rcub_farfar_5028 .