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Densitometric determination of omeprazole, pantoprazole, and their impurities in pharmaceuticals
dc.creator | Agbaba, Danica | |
dc.creator | Novović, D | |
dc.creator | Karljiković-Rajić, Katarina | |
dc.creator | Marinković, Valentina | |
dc.date.accessioned | 2019-09-02T10:59:15Z | |
dc.date.available | 2019-09-02T10:59:15Z | |
dc.date.issued | 2004 | |
dc.identifier.issn | 0933-4173 | |
dc.identifier.uri | https://farfar.pharmacy.bg.ac.rs/handle/123456789/525 | |
dc.description.abstract | A method has been developed for separation of omeprazole and pantoprazole, and their impurities omeprazole sulfone and N-methylpantoprazole, by HPTLC. The mobile phase chloroform-2-propanol-25% ammonia-acetonitrile, 10.8 + 1.2 + 0.3 + 4 (v/v), enables good resolution of large excesses of the drugs from the possible impurities. Regression coefficients (r > 0.998), recovery (90.7-120.0%), and detection limit (0.025-0.05%) were validated and found to be satisfactory. The methods is convenient for quantitative analysis and purity control of the compounds. | en |
dc.publisher | Research Inst Medicinal Plants, Budakalasz | |
dc.rights | restrictedAccess | |
dc.source | Journal of Planar Chromatography - Modern TLC | |
dc.subject | planar chromatography | en |
dc.subject | omeprazole | en |
dc.subject | pantoprazole | en |
dc.subject | impurities | en |
dc.subject | pharmaceutical preparations | en |
dc.title | Densitometric determination of omeprazole, pantoprazole, and their impurities in pharmaceuticals | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Нововић, Д; Карљиковић-Рајић, Катарина; Маринковић, Валентина; Aгбаба, Даница; | |
dc.citation.volume | 17 | |
dc.citation.issue | 3 | |
dc.citation.spage | 169 | |
dc.citation.epage | 172 | |
dc.citation.other | 17(3): 169-172 | |
dc.citation.rank | M23 | |
dc.identifier.wos | 000222956100002 | |
dc.identifier.doi | 10.1556/JPC.17.2004.3.2 | |
dc.identifier.scopus | 2-s2.0-4043090664 | |
dc.type.version | publishedVersion |