Biopharmaceutical properties of adapalene loaded biocompatible microemulsions
Само за регистроване кориснике
2019
Конференцијски прилог (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Adapalene (ADA) belongs to the group of retinoids,
synthetic analogs of retinol, and it is used as a first line
therapy of mild to moderate acne, with a few exceptions
(1). However, dermal availability of ADA is limited due to
its poor aqueous solubility. In order to enhance the drug
penetration into target areas (i.e. hair follicles and
epidermis), several strategies, such as liposomes,
microemulsions (MEs), solid lipid microparticles,
nanostructured lipid carriers etc., were proposed recently.
MEs have been reported as a promising tool for topical drug
delivery because they combine several advantages over
conventional formulations, including ease of manufacture,
high solubilization potential for poorly soluble drugs,
reduced side effects, long-term stability and improved drug
penetration through/into the skin (2).
Извор:
3rd European Conference on Pharmaceutics, 25 to 26 March, 2019, Bologna, Italy, Abstract book, 2019Финансирање / пројекти:
- Развој микро- и наносистема као носача за лекове са антиинфламаторним деловањем и метода за њихову карактеризацију (RS-MESTD-Technological Development (TD or TR)-34031)
Институција/група
PharmacyTY - CONF AU - Bubić Pajić, Nataša AU - Nikolić, Ines AU - Dobričić, Vladimir AU - Savić, Snežana PY - 2019 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5456 AB - Adapalene (ADA) belongs to the group of retinoids, synthetic analogs of retinol, and it is used as a first line therapy of mild to moderate acne, with a few exceptions (1). However, dermal availability of ADA is limited due to its poor aqueous solubility. In order to enhance the drug penetration into target areas (i.e. hair follicles and epidermis), several strategies, such as liposomes, microemulsions (MEs), solid lipid microparticles, nanostructured lipid carriers etc., were proposed recently. MEs have been reported as a promising tool for topical drug delivery because they combine several advantages over conventional formulations, including ease of manufacture, high solubilization potential for poorly soluble drugs, reduced side effects, long-term stability and improved drug penetration through/into the skin (2). C3 - 3rd European Conference on Pharmaceutics, 25 to 26 March, 2019, Bologna, Italy, Abstract book T1 - Biopharmaceutical properties of adapalene loaded biocompatible microemulsions UR - https://hdl.handle.net/21.15107/rcub_farfar_5456 ER -
@conference{ author = "Bubić Pajić, Nataša and Nikolić, Ines and Dobričić, Vladimir and Savić, Snežana", year = "2019", abstract = "Adapalene (ADA) belongs to the group of retinoids, synthetic analogs of retinol, and it is used as a first line therapy of mild to moderate acne, with a few exceptions (1). However, dermal availability of ADA is limited due to its poor aqueous solubility. In order to enhance the drug penetration into target areas (i.e. hair follicles and epidermis), several strategies, such as liposomes, microemulsions (MEs), solid lipid microparticles, nanostructured lipid carriers etc., were proposed recently. MEs have been reported as a promising tool for topical drug delivery because they combine several advantages over conventional formulations, including ease of manufacture, high solubilization potential for poorly soluble drugs, reduced side effects, long-term stability and improved drug penetration through/into the skin (2).", journal = "3rd European Conference on Pharmaceutics, 25 to 26 March, 2019, Bologna, Italy, Abstract book", title = "Biopharmaceutical properties of adapalene loaded biocompatible microemulsions", url = "https://hdl.handle.net/21.15107/rcub_farfar_5456" }
Bubić Pajić, N., Nikolić, I., Dobričić, V.,& Savić, S.. (2019). Biopharmaceutical properties of adapalene loaded biocompatible microemulsions. in 3rd European Conference on Pharmaceutics, 25 to 26 March, 2019, Bologna, Italy, Abstract book. https://hdl.handle.net/21.15107/rcub_farfar_5456
Bubić Pajić N, Nikolić I, Dobričić V, Savić S. Biopharmaceutical properties of adapalene loaded biocompatible microemulsions. in 3rd European Conference on Pharmaceutics, 25 to 26 March, 2019, Bologna, Italy, Abstract book. 2019;. https://hdl.handle.net/21.15107/rcub_farfar_5456 .
Bubić Pajić, Nataša, Nikolić, Ines, Dobričić, Vladimir, Savić, Snežana, "Biopharmaceutical properties of adapalene loaded biocompatible microemulsions" in 3rd European Conference on Pharmaceutics, 25 to 26 March, 2019, Bologna, Italy, Abstract book (2019), https://hdl.handle.net/21.15107/rcub_farfar_5456 .