Show simple item record

dc.creatorAgbaba, Danica
dc.creatorVučićević, Katarina
dc.creatorMarinković, Valentina
dc.date.accessioned2019-09-02T10:59:46Z
dc.date.available2019-09-02T10:59:46Z
dc.date.issued2004
dc.identifier.issn0009-5893
dc.identifier.urihttps://farfar.pharmacy.bg.ac.rs/handle/123456789/546
dc.description.abstractA method has been established for separation of nisoldipine and impurities, for example reactants, products of side-reactions, and photodegradation products, by HPTLC on LiChrospher Si 60 F-254s plates with detection at 280 nm. The mobile phase, cyclohexane-ethyl acetate-toluene, 7.5:7.5:10 (v/v), enables acceptable resolution of nisoldipine, in large excess, and possible impurities. Regression coefficients (r greater than or equal to 0.997), recovery (98-108%), and determination limit (0.02-0.2%) were validated and found to be satisfactory. The method is convenient for quantitative analysis and purity control of nisoldipine in its raw material and dosage forms.en
dc.publisherSpringer Heidelberg, Heidelberg
dc.rightsrestrictedAccess
dc.sourceChromatographia
dc.subjectthin-layer chromatographyen
dc.subjectnisoldipine and impuritiesen
dc.subjectpharmaceutical preparationsen
dc.titleDetermination of nisoldipine and its impurities in pharmaceuticalsen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractВучићевић, Катарина; Aгбаба, Даница; Маринковић, Валентина;
dc.citation.volume60
dc.citation.issue3-4
dc.citation.spage223
dc.citation.epage227
dc.citation.other60(3-4): 223-227
dc.citation.rankM22
dc.identifier.wos000224100700014
dc.identifier.doi10.1365/s10337-004-0335-4
dc.identifier.scopus2-s2.0-4344560347
dc.identifier.rcubconv_1562
dc.type.versionpublishedVersion


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record