dc.creator | Agbaba, Danica | |
dc.creator | Vučićević, Katarina | |
dc.creator | Marinković, Valentina | |
dc.date.accessioned | 2019-09-02T10:59:46Z | |
dc.date.available | 2019-09-02T10:59:46Z | |
dc.date.issued | 2004 | |
dc.identifier.issn | 0009-5893 | |
dc.identifier.uri | https://farfar.pharmacy.bg.ac.rs/handle/123456789/546 | |
dc.description.abstract | A method has been established for separation of nisoldipine and impurities, for example reactants, products of side-reactions, and photodegradation products, by HPTLC on LiChrospher Si 60 F-254s plates with detection at 280 nm. The mobile phase, cyclohexane-ethyl acetate-toluene, 7.5:7.5:10 (v/v), enables acceptable resolution of nisoldipine, in large excess, and possible impurities. Regression coefficients (r greater than or equal to 0.997), recovery (98-108%), and determination limit (0.02-0.2%) were validated and found to be satisfactory. The method is convenient for quantitative analysis and purity control of nisoldipine in its raw material and dosage forms. | en |
dc.publisher | Springer Heidelberg, Heidelberg | |
dc.rights | restrictedAccess | |
dc.source | Chromatographia | |
dc.subject | thin-layer chromatography | en |
dc.subject | nisoldipine and impurities | en |
dc.subject | pharmaceutical preparations | en |
dc.title | Determination of nisoldipine and its impurities in pharmaceuticals | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Вучићевић, Катарина; Aгбаба, Даница; Маринковић, Валентина; | |
dc.citation.volume | 60 | |
dc.citation.issue | 3-4 | |
dc.citation.spage | 223 | |
dc.citation.epage | 227 | |
dc.citation.other | 60(3-4): 223-227 | |
dc.citation.rank | M22 | |
dc.identifier.wos | 000224100700014 | |
dc.identifier.doi | 10.1365/s10337-004-0335-4 | |
dc.identifier.scopus | 2-s2.0-4344560347 | |
dc.type.version | publishedVersion | |