Chemical composition and antimicrobial activity Chemical Composition and Antimicrobial Activity of the Essential Oil from Cultivated Satureja horvatii Silić (Lamiaceae)
Abstract
In this study the chemical composition and antimicrobial activity of the essential oils of Satureja horvatii cultivated plants (Belgrade, Serbia) were characterized. S. horvatii is an endemo-relict species of Montenegro. The essential oils were isolated, from the aerial parts of the plants at different phenological stages, by hydrodistillation and analyzed by GC and GC/MS. Chemical compositions of the S. horvatii oils showed differences between the plants at different phenological stages. The main compounds of the essential oil from plants at the flowering stage were linalool (53.5%), thymol (17.9%), and α-terpineol (8.5%). At the stage of full fruiting the percentage of linalool (58.4–59.5%) and α-terpineol (11.8-12.3%) increased, while those of thymol (4.6–7.6%) significantly decreased. The antimicrobial activity of tested oils was evaluated against ten standard strains of microorganisms.The working solutions of essential oils (40 μL/mL) were prepared by dissolving the essential oils... (EOs) in DMSO and subsequent mixing with Müller–Hinton or Sabouraud dextrose broth. The EOs were tested in the final concetration range of 0.313 - 20.000 μL/mL. All analyzed oils showed the greatest and uniform antimicrobial activity against the yeast (Candida albicans). The essential oil isolated from plant in the flowering stage showed the maximum activity against Staphylococcus epidermidis and Staphylococcus aureus. This oil exhibited moderate activity against the Enterococcus faecalis and weak activity against the other microorganisms. Oils isolated from plants at fruiting stage showed moderate activity against Staphylococcus epidermidis, Staphylococcus aureus and Pseudomonas aeruginosa and weak activity against the other microorganisms.
Keywords:
Satureja horvatii cultivate / linalool / thymol / α-terpineol / Staphylococcus epidermidis / Staphylococcus aureus / Pseudomonas aeruginosaSource:
Fourth International Meeting on Pharmacy & Pharmaceutical Sciences, Abstract book, 2014, 70-70Publisher:
- Marmara University Faculty of Pharmacy
Funding / projects:
- Investigation on the medicinal plants: morphological, chemical and pharmacological characterisation (RS-MESTD-Basic Research (BR or ON)-173021)
- Plant Biodiversity of Serbia and the Balkans - assesment, sustainable use and protection (RS-MESTD-Basic Research (BR or ON)-173030)
Note:
- Fourth International Meeting on Pharmacy & Pharmaceutical Sciences, 18-21 September 2014, Istanbul, Turkey
Collections
Institution/Community
PharmacyTY - CONF AU - Milenković, Marina AU - Ristić, Mihailo AU - Lakušić, Dmitar AU - Slavkovska, Violeta AU - Lakušić, Branislava PY - 2014 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5528 AB - In this study the chemical composition and antimicrobial activity of the essential oils of Satureja horvatii cultivated plants (Belgrade, Serbia) were characterized. S. horvatii is an endemo-relict species of Montenegro. The essential oils were isolated, from the aerial parts of the plants at different phenological stages, by hydrodistillation and analyzed by GC and GC/MS. Chemical compositions of the S. horvatii oils showed differences between the plants at different phenological stages. The main compounds of the essential oil from plants at the flowering stage were linalool (53.5%), thymol (17.9%), and α-terpineol (8.5%). At the stage of full fruiting the percentage of linalool (58.4–59.5%) and α-terpineol (11.8-12.3%) increased, while those of thymol (4.6–7.6%) significantly decreased. The antimicrobial activity of tested oils was evaluated against ten standard strains of microorganisms.The working solutions of essential oils (40 μL/mL) were prepared by dissolving the essential oils (EOs) in DMSO and subsequent mixing with Müller–Hinton or Sabouraud dextrose broth. The EOs were tested in the final concetration range of 0.313 - 20.000 μL/mL. All analyzed oils showed the greatest and uniform antimicrobial activity against the yeast (Candida albicans). The essential oil isolated from plant in the flowering stage showed the maximum activity against Staphylococcus epidermidis and Staphylococcus aureus. This oil exhibited moderate activity against the Enterococcus faecalis and weak activity against the other microorganisms. Oils isolated from plants at fruiting stage showed moderate activity against Staphylococcus epidermidis, Staphylococcus aureus and Pseudomonas aeruginosa and weak activity against the other microorganisms. PB - Marmara University Faculty of Pharmacy C3 - Fourth International Meeting on Pharmacy & Pharmaceutical Sciences, Abstract book T1 - Chemical composition and antimicrobial activity Chemical Composition and Antimicrobial Activity of the Essential Oil from Cultivated Satureja horvatii Silić (Lamiaceae) SP - 70 EP - 70 UR - https://hdl.handle.net/21.15107/rcub_farfar_5528 ER -
@conference{ author = "Milenković, Marina and Ristić, Mihailo and Lakušić, Dmitar and Slavkovska, Violeta and Lakušić, Branislava", year = "2014", abstract = "In this study the chemical composition and antimicrobial activity of the essential oils of Satureja horvatii cultivated plants (Belgrade, Serbia) were characterized. S. horvatii is an endemo-relict species of Montenegro. The essential oils were isolated, from the aerial parts of the plants at different phenological stages, by hydrodistillation and analyzed by GC and GC/MS. Chemical compositions of the S. horvatii oils showed differences between the plants at different phenological stages. The main compounds of the essential oil from plants at the flowering stage were linalool (53.5%), thymol (17.9%), and α-terpineol (8.5%). At the stage of full fruiting the percentage of linalool (58.4–59.5%) and α-terpineol (11.8-12.3%) increased, while those of thymol (4.6–7.6%) significantly decreased. The antimicrobial activity of tested oils was evaluated against ten standard strains of microorganisms.The working solutions of essential oils (40 μL/mL) were prepared by dissolving the essential oils (EOs) in DMSO and subsequent mixing with Müller–Hinton or Sabouraud dextrose broth. The EOs were tested in the final concetration range of 0.313 - 20.000 μL/mL. All analyzed oils showed the greatest and uniform antimicrobial activity against the yeast (Candida albicans). The essential oil isolated from plant in the flowering stage showed the maximum activity against Staphylococcus epidermidis and Staphylococcus aureus. This oil exhibited moderate activity against the Enterococcus faecalis and weak activity against the other microorganisms. Oils isolated from plants at fruiting stage showed moderate activity against Staphylococcus epidermidis, Staphylococcus aureus and Pseudomonas aeruginosa and weak activity against the other microorganisms.", publisher = "Marmara University Faculty of Pharmacy", journal = "Fourth International Meeting on Pharmacy & Pharmaceutical Sciences, Abstract book", title = "Chemical composition and antimicrobial activity Chemical Composition and Antimicrobial Activity of the Essential Oil from Cultivated Satureja horvatii Silić (Lamiaceae)", pages = "70-70", url = "https://hdl.handle.net/21.15107/rcub_farfar_5528" }
Milenković, M., Ristić, M., Lakušić, D., Slavkovska, V.,& Lakušić, B.. (2014). Chemical composition and antimicrobial activity Chemical Composition and Antimicrobial Activity of the Essential Oil from Cultivated Satureja horvatii Silić (Lamiaceae). in Fourth International Meeting on Pharmacy & Pharmaceutical Sciences, Abstract book Marmara University Faculty of Pharmacy., 70-70. https://hdl.handle.net/21.15107/rcub_farfar_5528
Milenković M, Ristić M, Lakušić D, Slavkovska V, Lakušić B. Chemical composition and antimicrobial activity Chemical Composition and Antimicrobial Activity of the Essential Oil from Cultivated Satureja horvatii Silić (Lamiaceae). in Fourth International Meeting on Pharmacy & Pharmaceutical Sciences, Abstract book. 2014;:70-70. https://hdl.handle.net/21.15107/rcub_farfar_5528 .
Milenković, Marina, Ristić, Mihailo, Lakušić, Dmitar, Slavkovska, Violeta, Lakušić, Branislava, "Chemical composition and antimicrobial activity Chemical Composition and Antimicrobial Activity of the Essential Oil from Cultivated Satureja horvatii Silić (Lamiaceae)" in Fourth International Meeting on Pharmacy & Pharmaceutical Sciences, Abstract book (2014):70-70, https://hdl.handle.net/21.15107/rcub_farfar_5528 .