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Deprescribing potential of commonly used medications among community-dwelling older adults: insights from a pharmacist’s geriatric assessment
dc.creator | Bužančić, Iva | |
dc.creator | Držaić, Margita | |
dc.creator | Kummer, Ingrid | |
dc.creator | Ortner Hadžiabdić, Maja | |
dc.creator | Brkić, Jovana | |
dc.creator | Fialová, Daniela | |
dc.date.accessioned | 2024-03-26T14:45:57Z | |
dc.date.available | 2024-03-26T14:45:57Z | |
dc.date.issued | 2024 | |
dc.identifier.issn | 2045-2322 | |
dc.identifier.uri | https://farfar.pharmacy.bg.ac.rs/handle/123456789/5571 | |
dc.description.abstract | Pharmacist’s geriatric assessment can provide valuable insights into potential deprescribing targets, while including important information on various health-related domains. Data collected from a geriatric assessment questionnaire, for 388 patients, from the Croatian cohort of the EuroAgeism H2020 ESR 7 international project, along with guideline-based deprescribing criteria, were used to analyse potentially inappropriate prescribing of four medication groups (benzodiazepines (BZN), proton pump inhibitors (PPI), opioids, and non-steroidal anti-inflammatory drugs (NSAID)), and to assess the deprescribing potential. Binary logistic regression was used to explore the effects of age, gender, number of medicines and diagnoses, self-reported health, frailty score, and healthcare utilization on the likelihood of needing deprescribing. More than half of participants (n = 216, 55.2%) are candidates for deprescribing, with 31.1% of PPI, 74.8% of NSAID, 75% of opioid, and 96.1% of BZN users meeting at least one criterion. Most common criteria for deprescribing were inappropriately long use and safety concerns. Women (aOR = 2.58; p < 0.001), those reporting poor self-reported health (aOR = 5.14; p < 0.001), and those exposed to polypharmacy (aOR = 1.29; p < 0.001) had higher odds of needing to have medicines deprescribed. The high rate of deprescribing potential warrants prompt action to increase patient safety and decrease polypharmacy. Pharmacist’s geriatric assessment and deprescribing-focused medication review could be used to lead a personalised approach. | |
dc.publisher | Nature Research | |
dc.relation | The EuroAgeism H2020 project (ESR7 project) | |
dc.relation | The European Union research and innovation program | |
dc.relation | The Grant Agreement of the Marie Skłodowska-Curie Founda- tion Number MSCF-ITN-764632 | |
dc.relation | The Grants: InoMed, Reg. No CZ.02.1.01/0.0/0.0/18_069/0010046 | |
dc.relation | The European Horizon 2020 I-CARE4OLD Grant No 965341 | |
dc.relation | START/MED/093 EN.02.2.69/0.0/0.0/19_073/0016935 | |
dc.relation | SVV 260 551 Grant | |
dc.relation | Cooperatio research program of the Faculty of Pharmacy, Charles University (Research Unit: “Ageing, Polypharmacotherapy and Changes in Therapeutic Value of Drugs in the Aged’’, KSKF-I. | |
dc.relation | NETPHARM project CZ.02.01.01/00/22_008/0004607 | |
dc.rights | openAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.source | Scientific Reports | |
dc.subject | Geriatrics | |
dc.subject | Deprescribing | |
dc.subject | Geriatric assessment | |
dc.subject | Healthy ageing | |
dc.subject | Polypharmacy | |
dc.title | Deprescribing potential of commonly used medications among community-dwelling older adults: insights from a pharmacist’s geriatric assessment | |
dc.type | article | |
dc.rights.license | BY | |
dc.citation.volume | 14 | |
dc.citation.issue | 1 | |
dc.citation.spage | 6235 | |
dc.identifier.wos | 001185787000054 | |
dc.identifier.doi | 10.1038/s41598-024-56780-1 | |
dc.identifier.pmid | 38485992 | |
dc.identifier.scopus | 2-s2.0-85187891254 | |
dc.identifier.fulltext | http://farfar.pharmacy.bg.ac.rs/bitstream/id/15725/Deprescribing_potential_of_pub_2024.pdf | |
dc.type.version | publishedVersion |