Overcoming the low solubility of novel pyrazoloquinolinone ligand (CW-02-79) by combination of drug-phospholipid complex and nanoemulsion technology: design and physicochemical evaluation
Само за регистроване кориснике
2024
Аутори
Stanković, TijanaIlić, Tanja
Petković, Miloš
Pantelić, Ivana
Dobričić, Vladimir
Cook, James M.
Savić, Miroslav
Savić, Snežana
Конференцијски прилог (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The low aqueous and oil solubility of the novel
pyrazoloquinolinone ligand (CW-02-79) with significant
binding affinity for sigma-2 receptors in the brain hinders
the development of conventional parenteral formulations
and thus a comprehensive evaluation of its efficacy and
safety. ...
Кључне речи:
CW-02-79 / drug-phospholipid complex / nanoemulsion / pyrazoloquinolinoneИзвор:
14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 18 - 21 March 2024, Vienna, Austria, 2024Издавач:
- International Society of Drug Delivery Sciences and Technology (APGI)
- International Association for Pharmaceutical Technology (APV)
- Italian Society of Technology and Legislation (S.T.E.L.F)
Финансирање / пројекти:
- NanoCellEmoCog - Neuroimmune aspects of mood, anxiety and cognitive effects of leads/drug candidates acting at GABAA and/or sigma-2 receptors: In vitro/in vivo delineation by nano- and hiPSC-based platform (RS-ScienceFundRS-Ideje-7749108)
Напомена:
- Poster presentation: https://farfar.pharmacy.bg.ac.rs/handle/123456789/5578
Повезане информације:
- Повезани садржај
https://farfar.pharmacy.bg.ac.rs/handle/123456789/5578
Институција/група
PharmacyTY - CONF AU - Stanković, Tijana AU - Ilić, Tanja AU - Petković, Miloš AU - Pantelić, Ivana AU - Dobričić, Vladimir AU - Cook, James M. AU - Savić, Miroslav AU - Savić, Snežana PY - 2024 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/5577 AB - The low aqueous and oil solubility of the novel pyrazoloquinolinone ligand (CW-02-79) with significant binding affinity for sigma-2 receptors in the brain hinders the development of conventional parenteral formulations and thus a comprehensive evaluation of its efficacy and safety. ... PB - International Society of Drug Delivery Sciences and Technology (APGI) PB - International Association for Pharmaceutical Technology (APV) PB - Italian Society of Technology and Legislation (S.T.E.L.F) C3 - 14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 18 - 21 March 2024, Vienna, Austria T1 - Overcoming the low solubility of novel pyrazoloquinolinone ligand (CW-02-79) by combination of drug-phospholipid complex and nanoemulsion technology: design and physicochemical evaluation UR - https://hdl.handle.net/21.15107/rcub_farfar_5577 ER -
@conference{ author = "Stanković, Tijana and Ilić, Tanja and Petković, Miloš and Pantelić, Ivana and Dobričić, Vladimir and Cook, James M. and Savić, Miroslav and Savić, Snežana", year = "2024", abstract = "The low aqueous and oil solubility of the novel pyrazoloquinolinone ligand (CW-02-79) with significant binding affinity for sigma-2 receptors in the brain hinders the development of conventional parenteral formulations and thus a comprehensive evaluation of its efficacy and safety. ...", publisher = "International Society of Drug Delivery Sciences and Technology (APGI), International Association for Pharmaceutical Technology (APV), Italian Society of Technology and Legislation (S.T.E.L.F)", journal = "14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 18 - 21 March 2024, Vienna, Austria", title = "Overcoming the low solubility of novel pyrazoloquinolinone ligand (CW-02-79) by combination of drug-phospholipid complex and nanoemulsion technology: design and physicochemical evaluation", url = "https://hdl.handle.net/21.15107/rcub_farfar_5577" }
Stanković, T., Ilić, T., Petković, M., Pantelić, I., Dobričić, V., Cook, J. M., Savić, M.,& Savić, S.. (2024). Overcoming the low solubility of novel pyrazoloquinolinone ligand (CW-02-79) by combination of drug-phospholipid complex and nanoemulsion technology: design and physicochemical evaluation. in 14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 18 - 21 March 2024, Vienna, Austria International Society of Drug Delivery Sciences and Technology (APGI).. https://hdl.handle.net/21.15107/rcub_farfar_5577
Stanković T, Ilić T, Petković M, Pantelić I, Dobričić V, Cook JM, Savić M, Savić S. Overcoming the low solubility of novel pyrazoloquinolinone ligand (CW-02-79) by combination of drug-phospholipid complex and nanoemulsion technology: design and physicochemical evaluation. in 14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 18 - 21 March 2024, Vienna, Austria. 2024;. https://hdl.handle.net/21.15107/rcub_farfar_5577 .
Stanković, Tijana, Ilić, Tanja, Petković, Miloš, Pantelić, Ivana, Dobričić, Vladimir, Cook, James M., Savić, Miroslav, Savić, Snežana, "Overcoming the low solubility of novel pyrazoloquinolinone ligand (CW-02-79) by combination of drug-phospholipid complex and nanoemulsion technology: design and physicochemical evaluation" in 14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 18 - 21 March 2024, Vienna, Austria (2024), https://hdl.handle.net/21.15107/rcub_farfar_5577 .