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Koncentracija magnezijuma u serumu i urinu kod bolesnika sa akutnim i hroničnim plućnim bolestima

dc.creatorNagorni-Obradović, Ljudmila
dc.creatorIgnjatović, Svetlana
dc.creatorPetrović, Vesna
dc.creatorMitić-Milikić, Marija
dc.date.accessioned2019-09-02T11:00:17Z
dc.date.available2019-09-02T11:00:17Z
dc.date.issued2004
dc.identifier.issn0354-3447
dc.identifier.urihttps://farfar.pharmacy.bg.ac.rs/handle/123456789/564
dc.description.abstractIn this study we determined magnesium concentration in serum and in 24-hour urine, at the start (To) and at the end of treatment (T1), in 56 patients with acute pulmonary disease (B1) and in 58 patients with chronic obstructive pulmonary disease - COPD (B2). In group B1 there was disbalance of Mg in serum in 14-25% patients at the start of treatment (To) which decreased significantly at the end of treatment (T1) and persisted in 4-7.1% patients (p lt 0.05). In group B2 distribution of normal, decreased and increased values of Mg in serum was similar in patients in period To and T1 (p > 0.05). In group B1, 9 (16.1%) patients had hypomagnesemia at the start of treatment (To), which was accompanied by increased concentration of Mg in 24-hour urine of only 4 (7.2%) patients. There is a possibility that there was extrarenal elimination of Mg in patients with acute pulmonary disease or there was some kind of transcellular distribution. In group B2 in period To, there was proportional ratio between hypomagnesemia (12-20.7% patients) and increased concentration of Mg in 24-hour urine (20 -34.5% patients). This could be because of renal loss. Simultaneous determination and follow up of magnesium in serum and in 24-hour urine can give us reliable information about homeostasis of this electrolyte in acute and chronic pulmonary diseases.en
dc.description.abstractU ovom radu određivana je koncentracija magnezijuma u serumu i u 24-urinu, na početku (To) i na kraju hospitalnog lečenja (T1) kod 56 bolesnika sa akutnim plućnim bolestima (B1) i kod 58 sa hroničnim plućnim bolestima (B2). U grupi B1 postojao je disbalans Mg u serumu kod 14-25% bolesnika na početku lečenja (To) koji se značajno smanjio na kraju lečenja (T1) i postojao je kod 4-7,1% bolesnika (p lt 0,05). U grupi B2 distribucija normalnih, snizenih i povišenih vrednosti Mg u serumu bila je slična u periodu To i T1 (p> 0,05). Hipomagnezemiju u grupi B1 imalo je 9 (16,1%) bolesnika na početku lečenja (To) što je bilo praćeno povećanom koncentracijom Mg u 24-časovnom urinu samo kod 4 (7,2%) bolesnika. Ovo je bilo moguće zbog ekstrarenalnog gubitka elektrolita ili je došlo do transcelularne preraspodele. U grupi B2 u periodu To postojao je proporcionalni odnos hipomagnezemije (12,0-20,7% bolesnika) sa povećanom koncentracijom Mg u 24-časovnom urinu (20,0-34,5% bolesnika). Ovo je bilo moguće zbog renalne eliminacije elektrolita. Istovremeno određivanje i praćenje magnezijuma u serumu i 24-časovnom urinu daje pouzdane informacije o homeostazi ovog elektrolita kod akutnih i hroničnih plućnih bolesti.sr
dc.publisherDruštvo medicinskih biohemičara Srbije i Crne Gore, Beograd i Univerzitet u Beogradu - Farmaceutski fakultet, Beograd
dc.rightsopenAccess
dc.sourceJugoslovenska medicinska biohemija
dc.subjectmagnesiumen
dc.subjectserumen
dc.subjecturineen
dc.subjectpulmonary diseaseen
dc.subjectmagnezijumsr
dc.subjectserumsr
dc.subjecturinsr
dc.subjectplućne bolestisr
dc.titleMagnesium serum and urine concentration in patients with acute and chronic pulmonary diseaseen
dc.titleKoncentracija magnezijuma u serumu i urinu kod bolesnika sa akutnim i hroničnim plućnim bolestimasr
dc.typearticle
dc.rights.licenseARR
dcterms.abstractИгњатовић, Светлана; Нагорни-Обрадовић, Људмила; Митић-Миликић, Марија; Петровић, Весна; Концентрација магнезијума у серуму и урину код болесника са акутним и хроничним плућним болестима; Концентрација магнезијума у серуму и урину код болесника са акутним и хроничним плућним болестима;
dc.citation.volume23
dc.citation.issue2
dc.citation.spage155
dc.citation.epage160
dc.citation.other23(2): 155-160
dc.citation.rankM23
dc.identifier.doi10.2298/JMH0402155N
dc.identifier.scopus2-s2.0-2542462079
dc.identifier.fulltexthttps://farfar.pharmacy.bg.ac.rs//bitstream/id/2078/562.pdf
dc.identifier.rcubconv_837
dc.type.versionpublishedVersion


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