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dc.creatorLučić, Branka
dc.creatorRadulović, Dušanka
dc.creatorVujić, Zorica
dc.creatorAgbaba, Danica
dc.date.accessioned2019-09-02T11:00:25Z
dc.date.available2019-09-02T11:00:25Z
dc.date.issued2005
dc.identifier.issn0933-4173
dc.identifier.urihttps://farfar.pharmacy.bg.ac.rs/handle/123456789/570
dc.description.abstractA method for chromatographic separation of the enantiomers of (+/-)-metoprolol tartrate (+/- MeT) employing a chiral mobile phase additive (CMPA) is described. By using silica gel plates previously impregnated with the mobile phase (ethanol-water, 70 + 30, v/v) containing D-(-)-tartaric acid as chiral selector, direct separation of the enantiomers of +/- MeT was achieved. The results of experiments with different concentrations of D-(-)-tartaric acid (5.8, 11.6, and 23 mmol L-1) revealed that the best resolution of the enantiomers of +/- MeT was achieved with 11.6 mm D-(-)-tartaric acid in both the mobile phase and the impregnation solution, at 25 2 degrees C.en
dc.publisherResearch Inst Medicinal Plants, Budakalasz
dc.rightsrestrictedAccess
dc.sourceJournal of Planar Chromatography - Modern TLC
dc.subjectTLCen
dc.subjectchiral separationen
dc.subjectmetoprolol tartrateen
dc.subjectD-(-)-tartaric aciden
dc.titleDirect separation of the enantiomers of (+/-)-metoprolol tartrate on impregnated TLC plates with D-(-)-tartaric acid as a chiral selectoren
dc.typearticle
dc.rights.licenseARR
dcterms.abstractРадуловић, Душанка; Лучић, Бранка; Вујић, Зорица; Aгбаба, Даница;
dc.citation.volume18
dc.citation.issue104
dc.citation.spage294
dc.citation.epage299
dc.citation.other18(104): 294-299
dc.citation.rankM23
dc.identifier.wos000231689200008
dc.identifier.doi10.1556/JPC.18.2005.4.8
dc.identifier.scopus2-s2.0-24344454332
dc.identifier.rcubconv_1656
dc.type.versionpublishedVersion


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