dc.creator | Živanović, L | |
dc.creator | Zečević, Mira | |
dc.creator | Marković, S | |
dc.creator | Petrović, S | |
dc.creator | Ivanović, I | |
dc.date.accessioned | 2019-09-02T11:00:31Z | |
dc.date.available | 2019-09-02T11:00:31Z | |
dc.date.issued | 2005 | |
dc.identifier.issn | 0021-9673 | |
dc.identifier.uri | https://farfar.pharmacy.bg.ac.rs/handle/123456789/573 | |
dc.description.abstract | In this paper, there was developed a sensitive, precise and accurate reversed-phase liquid chromatographic (RP-HPLC) method and validated for simultaneous determination of lidocaine hydrochloride, dexamethasone acetate (DA) and calcium dobesilate (CD) in suppositories and ointment. Also there was achieved a parallel analysis of buthylhydroxyanisol, as a preservative, and hydroquinone, as a degradation product of calcium dobesilate, present in these dosage forms. The relative standard deviation (RSD) values for all five compounds indicated a good precision and accuracy of the RP-HPLC method. Method is selective, sensitive and reproducible with good recovery values and can be applied in simultaneous determination of all mentioned compounds. | en |
dc.publisher | Elsevier Science BV, Amsterdam | |
dc.rights | restrictedAccess | |
dc.source | Journal of Chromatography A | |
dc.subject | liquid chromatography | en |
dc.subject | validation | en |
dc.subject | lidocaine hydrochloride | en |
dc.subject | dexamethasone acetate | en |
dc.subject | calcium dobesilate | en |
dc.subject | buthylhydroxyanisol | en |
dc.subject | hydroquinone | en |
dc.title | Validation of liquid chromatographic method for analysis of lidocaine hydrochloride, dexamethasone acetate, calcium dobesilate, buthylhydroxyanisol and degradation product hydroquinone in suppositories and ointment | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Зечевић, Мира; Ивановић, И; Живановић, Л; Петровић, С; Марковић, С; | |
dc.citation.volume | 1088 | |
dc.citation.issue | 1-2 | |
dc.citation.spage | 182 | |
dc.citation.epage | 186 | |
dc.citation.other | 1088(1-2): 182-186 | |
dc.citation.rank | aM21 | |
dc.identifier.wos | 000231185900023 | |
dc.identifier.doi | 10.1016/j.chroma.2005.04.049 | |
dc.identifier.pmid | 16130749 | |
dc.identifier.scopus | 2-s2.0-23044514374 | |
dc.type.version | publishedVersion | |