Приказ основних података о документу

dc.creatorNovaković, J
dc.creatorAgbaba, Danica
dc.creatorVladimirov, S
dc.creatorŽivanov-Stakić, Dobrila
dc.date.accessioned2019-09-02T10:47:24Z
dc.date.available2019-09-02T10:47:24Z
dc.date.issued1990
dc.identifier.issn0731-7085
dc.identifier.urihttps://farfar.pharmacy.bg.ac.rs/handle/123456789/57
dc.description.abstractA densitometric method for determination of complex mixtures of conjugated oestrogens in raw material and tablets was developed. The proposed procedure comprised hydrolysis of sodium sulphate esters of oestrone, equilin, 17α-oestradiol, equilenin, 17α-dihydroequilin and 17α-dihydroequilenin, the chloroform extraction of free oestrogens and methyltestosterone (internal standard) and separation on TLC plates using chloroform-cyclohexane-dioxane-triethyl-amine (4.5:4.1:0.6, v/v) as the solvent for development. Quantitative assay was achieved by direct scanning of the oestrogen spots at 280 nm. The proposed method is simple, rapid, reproducible and adequate to control the content of conjugated oestrogens in the raw material and in pharmaceutical preparations.en
dc.rightsrestrictedAccess
dc.sourceJournal of Pharmaceutical and Biomedical Analysis
dc.subjectConjugated oestrogensen
dc.subjectdensitometryen
dc.subjectquantitative assayen
dc.subjectraw materialen
dc.subjectsample preparation.en
dc.subjectTLC separationen
dc.titleDensitometric determination of conjugated oestrogens in the raw material and in pharmaceutical preparationsen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractЖиванов-Стакић, Добрила; Новаковић, Ј; Aгбаба, Даница; Владимиров, С;
dc.citation.volume8
dc.citation.issue3
dc.citation.spage253
dc.citation.epage257
dc.citation.other8(3): 253-257
dc.identifier.doi10.1016/0731-7085(90)80034-M
dc.identifier.scopus2-s2.0-0025108296
dc.type.versionpublishedVersion


Документи

Thumbnail

Овај документ се појављује у следећим колекцијама

Приказ основних података о документу