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dc.creatorOdović, Jadranka
dc.creatorStojimirović, Biljana
dc.creatorAleksić, Mirjana
dc.creatorMilojković-Opsenica, Dušanka
dc.creatorTešić, Živoslav
dc.date.accessioned2019-09-02T11:00:47Z
dc.date.available2019-09-02T11:00:47Z
dc.date.issued2005
dc.identifier.issn0933-4173
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/584
dc.description.abstractThe behavior of five ACE inhibitors and their active degradation products in salting-out thin-layer chromatography (SO TLC) has been examined on silica gel, cellulose, and polyacrylonitrile (PAN) with aqueous ammonium sulfate solutions of different concentration as mobile phases. It was found that increasing the concentration of the salt in the mobile phase led to increased R-M values for all the substances. Linear relationships were established between salt concentration and R-M values and regression data of the plots obtained were used to determine the lipophilicity R-M(0) and C-0. Lipophilicity determined in this way was correlated with calculated log P values. For comparison of these results with chromatographic behavior in conventional RP TLC, the examined substances were subjected to thin-layer chromatography on RP-18 silica gel with methanol-water mobile phases.en
dc.publisherResearch Inst Medicinal Plants, Budakalasz
dc.rightsrestrictedAccess
dc.sourceJournal of Planar Chromatography - Modern TLC
dc.subjectsalting-out TLCen
dc.subjectACE inhibitorsen
dc.subjectsilica gelen
dc.subjectcelluloseen
dc.subjectpolyacrylonitrile (PAN) adsorbenten
dc.subjectRP-18 silicaen
dc.titleExamination of the hydrophobicity of ACE inhibitors and their active metabolites by salting-out thin-layer chromatographyen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractСтојимировић, Биљана; Aлексић, М.Б.; Тешић, Живослав; Милојковић-Опсеница, Душанка; Одовић, Јадранка;
dc.citation.volume18
dc.citation.issue102
dc.citation.spage98
dc.citation.epage103
dc.citation.other18(102): 98-103
dc.citation.rankM23
dc.identifier.wos000229721000002
dc.identifier.doi10.1556/JPC.18.2005.2.2
dc.identifier.scopus2-s2.0-20444417755
dc.identifier.rcubconv_1627
dc.type.versionpublishedVersion


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