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dc.creatorKundaković, Tatjana
dc.creatorStanojković, Tatjana
dc.creatorJuranić, Zorica
dc.creatorKovačević, Nada
dc.date.accessioned2019-09-02T11:00:56Z
dc.date.available2019-09-02T11:00:56Z
dc.date.issued2005
dc.identifier.issn0031-7144
dc.identifier.urihttps://farfar.pharmacy.bg.ac.rs/handle/123456789/590
dc.description.abstractThe cytotoxicity and antioxidant properties of herb extracts of Achillea alexandri-regis were studied. Combined chloroform and ethylacetate extracts exhibited a pronounced cytotoxic effect against HeLa cancer cells (IC50 = 25.92 +/- 4.96 mu g/ml), and lower cytotoxicity against K562 leukemia cells (IC50 = 48.59 +/- 18.31 mu g/ml). The methanol extract was found to be a moderately cytotoxic in vitro agent against HeLa and K562 cells. No suppressive activity was detected on non-malignant peripheral blood mononuclear cells (PBMC). The antioxidant activity of the methanol extract was assessed by DPPH radical scavenging. The methanol extract of A. alexandri-regis showed concentration dependent DPPH radical scavenging activity with IC50 = 36.14 +/- 0.05en
dc.publisherGovi-Verlag Pharmazeutischer Verlag Gmbh, Eschborn
dc.rightsrestrictedAccess
dc.sourcePharmazie
dc.titleCytotoxic and antioxidant activity of Achillea alexandri-regisen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractКовачевић, Нада; Кундаковић, Татјана; Станојковић, Татјана; Јуранић, Зорица;
dc.citation.volume60
dc.citation.issue4
dc.citation.spage319
dc.citation.epage320
dc.citation.other60(4): 319-320
dc.citation.rankM23
dc.identifier.wos000228532600018
dc.identifier.pmid15881617
dc.identifier.scopus2-s2.0-17644390239
dc.identifier.rcubhttps://hdl.handle.net/21.15107/rcub_farfar_590
dc.type.versionpublishedVersion


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