Coulometric determination of sulfadimethoxine and sulfafurazole.

Abstract

A chlorocoulometric method for determination of sulfadimethoxine and sulfafurazole in pharmaceutical preparation is proposed. The electrogeneration of chloride is carried out in the supporting electrolyte consisting of 0.5 mole x dm(-3) sulphuric acid and 0.2 mole x dm(-3) sodium chloride. The results obtained show that the method is accurate and reproducible and can be applied for determination of small quantities of sulfafurazole and sulfadimethoxine.