Synthesis of (-)-cytoxazone and (+)-epi-cytoxazone: The chiral pool approach
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2005
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Immunomodulator (-)-cytoxazone and its epimer (+)-epi-cytoxazone were synthesized starting from (D)-(-)-4-hydroxyphenylglycine. Homologation of the amino acid was achieved via the corresponding aldehyde, by a cyanohydrin reaction. The racemization of highly sensible amido aldehyde was efficiently suppressed when the oxidation of the parent aminoalcohol was performed by a modified Dess-Martin procedure.
Ključne reči:
amino alcohols / cyanohydrins / cytoxazone / oxazolinesIzvor:
Tenside Surfactants Detergents, 2005, 35, 3, 435-447Izdavač:
- Taylor & Francis Inc, Philadelphia
DOI: 10.1081/SCC-200048953
ISSN: 0039-7911
WoS: 000227372500012
Scopus: 2-s2.0-14644411112
Institucija/grupa
PharmacyTY - JOUR AU - Tokić-Vujošević, Zorana AU - Petrović, G AU - Rakić, B AU - Matović, Radomir AU - Saičić, Radomir N. PY - 2005 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/638 AB - Immunomodulator (-)-cytoxazone and its epimer (+)-epi-cytoxazone were synthesized starting from (D)-(-)-4-hydroxyphenylglycine. Homologation of the amino acid was achieved via the corresponding aldehyde, by a cyanohydrin reaction. The racemization of highly sensible amido aldehyde was efficiently suppressed when the oxidation of the parent aminoalcohol was performed by a modified Dess-Martin procedure. PB - Taylor & Francis Inc, Philadelphia T2 - Tenside Surfactants Detergents T1 - Synthesis of (-)-cytoxazone and (+)-epi-cytoxazone: The chiral pool approach VL - 35 IS - 3 SP - 435 EP - 447 DO - 10.1081/SCC-200048953 ER -
@article{ author = "Tokić-Vujošević, Zorana and Petrović, G and Rakić, B and Matović, Radomir and Saičić, Radomir N.", year = "2005", abstract = "Immunomodulator (-)-cytoxazone and its epimer (+)-epi-cytoxazone were synthesized starting from (D)-(-)-4-hydroxyphenylglycine. Homologation of the amino acid was achieved via the corresponding aldehyde, by a cyanohydrin reaction. The racemization of highly sensible amido aldehyde was efficiently suppressed when the oxidation of the parent aminoalcohol was performed by a modified Dess-Martin procedure.", publisher = "Taylor & Francis Inc, Philadelphia", journal = "Tenside Surfactants Detergents", title = "Synthesis of (-)-cytoxazone and (+)-epi-cytoxazone: The chiral pool approach", volume = "35", number = "3", pages = "435-447", doi = "10.1081/SCC-200048953" }
Tokić-Vujošević, Z., Petrović, G., Rakić, B., Matović, R.,& Saičić, R. N.. (2005). Synthesis of (-)-cytoxazone and (+)-epi-cytoxazone: The chiral pool approach. in Tenside Surfactants Detergents Taylor & Francis Inc, Philadelphia., 35(3), 435-447. https://doi.org/10.1081/SCC-200048953
Tokić-Vujošević Z, Petrović G, Rakić B, Matović R, Saičić RN. Synthesis of (-)-cytoxazone and (+)-epi-cytoxazone: The chiral pool approach. in Tenside Surfactants Detergents. 2005;35(3):435-447. doi:10.1081/SCC-200048953 .
Tokić-Vujošević, Zorana, Petrović, G, Rakić, B, Matović, Radomir, Saičić, Radomir N., "Synthesis of (-)-cytoxazone and (+)-epi-cytoxazone: The chiral pool approach" in Tenside Surfactants Detergents, 35, no. 3 (2005):435-447, https://doi.org/10.1081/SCC-200048953 . .