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Synthesis of (-)-cytoxazone and (+)-epi-cytoxazone: The chiral pool approach
dc.creator | Tokić-Vujošević, Zorana | |
dc.creator | Petrović, G | |
dc.creator | Rakić, B | |
dc.creator | Matović, Radomir | |
dc.creator | Saičić, Radomir N. | |
dc.date.accessioned | 2019-09-02T11:02:11Z | |
dc.date.available | 2019-09-02T11:02:11Z | |
dc.date.issued | 2005 | |
dc.identifier.issn | 0039-7911 | |
dc.identifier.uri | https://farfar.pharmacy.bg.ac.rs/handle/123456789/638 | |
dc.description.abstract | Immunomodulator (-)-cytoxazone and its epimer (+)-epi-cytoxazone were synthesized starting from (D)-(-)-4-hydroxyphenylglycine. Homologation of the amino acid was achieved via the corresponding aldehyde, by a cyanohydrin reaction. The racemization of highly sensible amido aldehyde was efficiently suppressed when the oxidation of the parent aminoalcohol was performed by a modified Dess-Martin procedure. | en |
dc.publisher | Taylor & Francis Inc, Philadelphia | |
dc.rights | restrictedAccess | |
dc.source | Tenside Surfactants Detergents | |
dc.subject | amino alcohols | en |
dc.subject | cyanohydrins | en |
dc.subject | cytoxazone | en |
dc.subject | oxazolines | en |
dc.title | Synthesis of (-)-cytoxazone and (+)-epi-cytoxazone: The chiral pool approach | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Ракић, Б; Саичић, Радомир Н.; Токић-Вујошевић, Зорана; Петровић, Г; Матовић, Радомир; | |
dc.citation.volume | 35 | |
dc.citation.issue | 3 | |
dc.citation.spage | 435 | |
dc.citation.epage | 447 | |
dc.citation.other | 35(3): 435-447 | |
dc.citation.rank | M23 | |
dc.identifier.wos | 000227372500012 | |
dc.identifier.doi | 10.1081/SCC-200048953 | |
dc.identifier.scopus | 2-s2.0-14644411112 | |
dc.type.version | publishedVersion |