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The urinary dehydroepiandrosterone, androsterone and etiocholanolone excretion of healthy women and women with benign and malignant breast disease

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1990
Authors
Ivanović, S
Agbaba, Danica
Živanov-Stakić, Dobrila
Konstantinović, I
Article (Published version)
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Abstract
The 24‐h urinary excretion of dehydroepiandrosterone, androsterone and etiocholanolone was followed in healthy women (n = 50) and in women with benign‐fibroadenoma (w = 32), microcysts (n= 32), macrocysts (n= 25) and malignant (n = 35) breast disease aged 35–50‐years. The data were analysed in three groups each covering 5 years (35‐39, 40–44 and 45–49). A significant decrease in the excretion of ethiocholanolone and dehydroepiandrosterone was found in women with benign and malignant breast disease when compared to controls. There was no significant decrease in androsterone excretion in women with benign and malignant breast disease when compared to a control group. A high correlation was found between excretion of etiocholanolone and its precursor dehydroepiandrosterone both in women with benign‐fibroadenoma (r= 0–7683) or macrocysts (r= 0–7337) and in women with malignant (r= 0–805) breast disease. Dehydroepiandrosterone and, in particular, etiocholanolone excretions were found to dec...rease significantly with age in women affected by malignant breast disease.

Source:
Journal of Clinical Pharmacy and Therapeutics, 1990, 15, 3, 213-219

DOI: 10.1111/j.1365-2710.1990.tb00377.x

ISSN: 0269-4727

Scopus: 2-s2.0-0025012169
[ Google Scholar ]
2
URI
https://farfar.pharmacy.bg.ac.rs/handle/123456789/74
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  • Radovi istraživača / Researchers’ publications
Institution/Community
Pharmacy
TY  - JOUR
AU  - Ivanović, S
AU  - Agbaba, Danica
AU  - Živanov-Stakić, Dobrila
AU  - Konstantinović, I
PY  - 1990
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/74
AB  - The 24‐h urinary excretion of dehydroepiandrosterone, androsterone and etiocholanolone was followed in healthy women (n = 50) and in women with benign‐fibroadenoma (w = 32), microcysts (n= 32), macrocysts (n= 25) and malignant (n = 35) breast disease aged 35–50‐years. The data were analysed in three groups each covering 5 years (35‐39, 40–44 and 45–49). A significant decrease in the excretion of ethiocholanolone and dehydroepiandrosterone was found in women with benign and malignant breast disease when compared to controls. There was no significant decrease in androsterone excretion in women with benign and malignant breast disease when compared to a control group. A high correlation was found between excretion of etiocholanolone and its precursor dehydroepiandrosterone both in women with benign‐fibroadenoma (r= 0–7683) or macrocysts (r= 0–7337) and in women with malignant (r= 0–805) breast disease. Dehydroepiandrosterone and, in particular, etiocholanolone excretions were found to decrease significantly with age in women affected by malignant breast disease.
T2  - Journal of Clinical Pharmacy and Therapeutics
T1  - The urinary dehydroepiandrosterone, androsterone and etiocholanolone excretion of healthy women and women with benign and malignant breast disease
VL  - 15
IS  - 3
SP  - 213
EP  - 219
DO  - 10.1111/j.1365-2710.1990.tb00377.x
ER  - 
@article{
author = "Ivanović, S and Agbaba, Danica and Živanov-Stakić, Dobrila and Konstantinović, I",
year = "1990",
abstract = "The 24‐h urinary excretion of dehydroepiandrosterone, androsterone and etiocholanolone was followed in healthy women (n = 50) and in women with benign‐fibroadenoma (w = 32), microcysts (n= 32), macrocysts (n= 25) and malignant (n = 35) breast disease aged 35–50‐years. The data were analysed in three groups each covering 5 years (35‐39, 40–44 and 45–49). A significant decrease in the excretion of ethiocholanolone and dehydroepiandrosterone was found in women with benign and malignant breast disease when compared to controls. There was no significant decrease in androsterone excretion in women with benign and malignant breast disease when compared to a control group. A high correlation was found between excretion of etiocholanolone and its precursor dehydroepiandrosterone both in women with benign‐fibroadenoma (r= 0–7683) or macrocysts (r= 0–7337) and in women with malignant (r= 0–805) breast disease. Dehydroepiandrosterone and, in particular, etiocholanolone excretions were found to decrease significantly with age in women affected by malignant breast disease.",
journal = "Journal of Clinical Pharmacy and Therapeutics",
title = "The urinary dehydroepiandrosterone, androsterone and etiocholanolone excretion of healthy women and women with benign and malignant breast disease",
volume = "15",
number = "3",
pages = "213-219",
doi = "10.1111/j.1365-2710.1990.tb00377.x"
}
Ivanović, S., Agbaba, D., Živanov-Stakić, D.,& Konstantinović, I.. (1990). The urinary dehydroepiandrosterone, androsterone and etiocholanolone excretion of healthy women and women with benign and malignant breast disease. in Journal of Clinical Pharmacy and Therapeutics, 15(3), 213-219.
https://doi.org/10.1111/j.1365-2710.1990.tb00377.x
Ivanović S, Agbaba D, Živanov-Stakić D, Konstantinović I. The urinary dehydroepiandrosterone, androsterone and etiocholanolone excretion of healthy women and women with benign and malignant breast disease. in Journal of Clinical Pharmacy and Therapeutics. 1990;15(3):213-219.
doi:10.1111/j.1365-2710.1990.tb00377.x .
Ivanović, S, Agbaba, Danica, Živanov-Stakić, Dobrila, Konstantinović, I, "The urinary dehydroepiandrosterone, androsterone and etiocholanolone excretion of healthy women and women with benign and malignant breast disease" in Journal of Clinical Pharmacy and Therapeutics, 15, no. 3 (1990):213-219,
https://doi.org/10.1111/j.1365-2710.1990.tb00377.x . .

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