Cytotoxicity in vitro of naphthazarin derivatives from Onosma arenaria

Kundaković, Tatjana; Stanojković, Tatjana; Juranić, Zorica; Kovačević, Nada

doi:10.1002/ptr.1899

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2006

Authors

Kundaković, Tatjana

Stanojković, Tatjana

Juranić, Zorica
Kovačević, Nada

Article (Published version)

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Abstract

The cytotoxicity of naphthazarin derivatives isolated from the roots of Onosma arenaria on human cervix adenocarcinoma cells (HeLa) and leukaemia K562 cells, as well on non-malignant peripheral blood mononuclear cells (PBMC) was studied. The results show that beta-hydroxyisovalerylalkannin, acetylalkannin and the pigment fraction exhibited high cytotoxicity in vitro against the tested cell lines, as well the healthy PBMC before or after activation with phytohaemagglutinin. Copyright

Keywords:

Onosma arenaria / cytotoxicity / acetylalkannin / beta-hydroxyisovalerylalkannin

Source:
Phytotherapy Research, 2006, 20, 7, 602-604

Publisher:

John Wiley & Sons Ltd, Chichester

DOI: 10.1002/ptr.1899

ISSN: 0951-418X

PubMed: 16718737

WoS: 000239216900015

Scopus: 2-s2.0-33746002347

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	11
	8

TY  - JOUR
AU  - Kundaković, Tatjana
AU  - Stanojković, Tatjana
AU  - Juranić, Zorica
AU  - Kovačević, Nada
PY  - 2006
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/813
AB  - The cytotoxicity of naphthazarin derivatives isolated from the roots of Onosma arenaria on human cervix adenocarcinoma cells (HeLa) and leukaemia K562 cells, as well on non-malignant peripheral blood mononuclear cells (PBMC) was studied. The results show that beta-hydroxyisovalerylalkannin, acetylalkannin and the pigment fraction exhibited high cytotoxicity in vitro against the tested cell lines, as well the healthy PBMC before or after activation with phytohaemagglutinin. Copyright
PB  - John Wiley & Sons Ltd, Chichester
T2  - Phytotherapy Research
T1  - Cytotoxicity in vitro of naphthazarin derivatives from Onosma arenaria
VL  - 20
IS  - 7
SP  - 602
EP  - 604
DO  - 10.1002/ptr.1899
ER  -

@article{
author = "Kundaković, Tatjana and Stanojković, Tatjana and Juranić, Zorica and Kovačević, Nada",
year = "2006",
abstract = "The cytotoxicity of naphthazarin derivatives isolated from the roots of Onosma arenaria on human cervix adenocarcinoma cells (HeLa) and leukaemia K562 cells, as well on non-malignant peripheral blood mononuclear cells (PBMC) was studied. The results show that beta-hydroxyisovalerylalkannin, acetylalkannin and the pigment fraction exhibited high cytotoxicity in vitro against the tested cell lines, as well the healthy PBMC before or after activation with phytohaemagglutinin. Copyright",
publisher = "John Wiley & Sons Ltd, Chichester",
journal = "Phytotherapy Research",
title = "Cytotoxicity in vitro of naphthazarin derivatives from Onosma arenaria",
volume = "20",
number = "7",
pages = "602-604",
doi = "10.1002/ptr.1899"
}

Kundaković, T., Stanojković, T., Juranić, Z.,& Kovačević, N.. (2006). Cytotoxicity in vitro of naphthazarin derivatives from Onosma arenaria. in Phytotherapy Research
John Wiley & Sons Ltd, Chichester., 20(7), 602-604.
https://doi.org/10.1002/ptr.1899

Kundaković T, Stanojković T, Juranić Z, Kovačević N. Cytotoxicity in vitro of naphthazarin derivatives from Onosma arenaria. in Phytotherapy Research. 2006;20(7):602-604.
doi:10.1002/ptr.1899 .

Kundaković, Tatjana, Stanojković, Tatjana, Juranić, Zorica, Kovačević, Nada, "Cytotoxicity in vitro of naphthazarin derivatives from Onosma arenaria" in Phytotherapy Research, 20, no. 7 (2006):602-604,
https://doi.org/10.1002/ptr.1899 . .