Compounds of phosphotungstic acid (WPA) containing the amino acids alanine (WPA-Ala) or glycine (WPA-Gly) as counter cations were synthesized and characterized by elemental analysis, thermal analysis, and IR spectroscopy. Cellular toxicity was assessed by the trypan blue exclusion method, and the antiviral activity of WPA and the modified WPA compounds was tested against herpes simplex viruses (HSV) type 1 and type 2. Biological assays indicate that the newly synthesized compounds exhibit no evident cytotoxic effects on Vero cells and negligible antiviral activity against HSV-1 and HSV-2.
TY - JOUR
AU - Kuntić, Vesna
AU - Stanojević, Maja
AU - Holclajtner-Antunović, Ivanka
AU - Uskoković-Marković, Snežana
AU - Mioč, Ubavka B.
AU - Todorović, Marija R.
AU - Jovanović, Tanja
AU - Vukojević, Vladana
PY - 2006
UR - http://farfar.pharmacy.bg.ac.rs/handle/123456789/837
AB - Compounds of phosphotungstic acid (WPA) containing the amino acids alanine (WPA-Ala) or glycine (WPA-Gly) as counter cations were synthesized and characterized by elemental analysis, thermal analysis, and IR spectroscopy. Cellular toxicity was assessed by the trypan blue exclusion method, and the antiviral activity of WPA and the modified WPA compounds was tested against herpes simplex viruses (HSV) type 1 and type 2. Biological assays indicate that the newly synthesized compounds exhibit no evident cytotoxic effects on Vero cells and negligible antiviral activity against HSV-1 and HSV-2.
PB - Springer Wien, Wien
T2 - Monatshefte für Chemie Chemical Monthly
T1 - Synthesis, characterization, and biological activity of amino acid derivatives of the heteropolytungstophosphoric acid
VL - 137
IS - 6
SP - 803
EP - 810
DO - 10.1007/s00706-006-0467-3
ER -
@article{
author = "Kuntić, Vesna and Stanojević, Maja and Holclajtner-Antunović, Ivanka and Uskoković-Marković, Snežana and Mioč, Ubavka B. and Todorović, Marija R. and Jovanović, Tanja and Vukojević, Vladana",
year = "2006",
url = "http://farfar.pharmacy.bg.ac.rs/handle/123456789/837",
abstract = "Compounds of phosphotungstic acid (WPA) containing the amino acids alanine (WPA-Ala) or glycine (WPA-Gly) as counter cations were synthesized and characterized by elemental analysis, thermal analysis, and IR spectroscopy. Cellular toxicity was assessed by the trypan blue exclusion method, and the antiviral activity of WPA and the modified WPA compounds was tested against herpes simplex viruses (HSV) type 1 and type 2. Biological assays indicate that the newly synthesized compounds exhibit no evident cytotoxic effects on Vero cells and negligible antiviral activity against HSV-1 and HSV-2.",
publisher = "Springer Wien, Wien",
journal = "Monatshefte für Chemie Chemical Monthly",
title = "Synthesis, characterization, and biological activity of amino acid derivatives of the heteropolytungstophosphoric acid",
volume = "137",
number = "6",
pages = "803-810",
doi = "10.1007/s00706-006-0467-3"
}
Kuntić, V., Stanojević, M., Holclajtner-Antunović, I., Uskoković-Marković, S., Mioč, U. B., Todorović, M. R., Jovanović, T.,& Vukojević, V. (2006). Synthesis, characterization, and biological activity of amino acid derivatives of the heteropolytungstophosphoric acid.
Monatshefte für Chemie Chemical Monthly
Springer Wien, Wien., 137(6), 803-810.
https://doi.org/10.1007/s00706-006-0467-3
Kuntić V, Stanojević M, Holclajtner-Antunović I, Uskoković-Marković S, Mioč UB, Todorović MR, Jovanović T, Vukojević V. Synthesis, characterization, and biological activity of amino acid derivatives of the heteropolytungstophosphoric acid. Monatshefte für Chemie Chemical Monthly. 2006;137(6):803-810
Kuntić Vesna, Stanojević Maja, Holclajtner-Antunović Ivanka, Uskoković-Marković Snežana, Mioč Ubavka B., Todorović Marija R., Jovanović Tanja, Vukojević Vladana, "Synthesis, characterization, and biological activity of amino acid derivatives of the heteropolytungstophosphoric acid" Monatshefte für Chemie Chemical Monthly, 137, no. 6 (2006):803-810,
https://doi.org/10.1007/s00706-006-0467-3 .
