Synthesis, characterization, and biological activity of amino acid derivatives of the heteropolytungstophosphoric acid
Само за регистроване кориснике
2006
Аутори
Kuntić, VesnaStanojević, Maja
Holclajtner-Antunović, Ivanka
Uskoković-Marković, Snežana
Mioč, Ubavka B.
Todorović, Marija R.
Jovanović, Tanja
Vukojević, Vladana
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Compounds of phosphotungstic acid (WPA) containing the amino acids alanine (WPA-Ala) or glycine (WPA-Gly) as counter cations were synthesized and characterized by elemental analysis, thermal analysis, and IR spectroscopy. Cellular toxicity was assessed by the trypan blue exclusion method, and the antiviral activity of WPA and the modified WPA compounds was tested against herpes simplex viruses (HSV) type 1 and type 2. Biological assays indicate that the newly synthesized compounds exhibit no evident cytotoxic effects on Vero cells and negligible antiviral activity against HSV-1 and HSV-2.
Кључне речи:
heteropoly compounds / amino acids / IR spectroscopy / cellular toxicity / antiviral activityИзвор:
Monatshefte für Chemie Chemical Monthly, 2006, 137, 6, 803-810Издавач:
- Springer Wien, Wien
Финансирање / пројекти:
- Структура, термодинамичке и електрохемијске особине материјала за конверзију енергије и нове технологије (RS-142047)
- Супстанце за фармацеутску употребу: моделирање, синтеза, физичко-хемијске и биолошке особине, степен чистоће и испитивање дозираних облика (RS-142072)
DOI: 10.1007/s00706-006-0467-3
ISSN: 0026-9247
WoS: 000239791700012
Scopus: 2-s2.0-33745013371
Институција/група
PharmacyTY - JOUR AU - Kuntić, Vesna AU - Stanojević, Maja AU - Holclajtner-Antunović, Ivanka AU - Uskoković-Marković, Snežana AU - Mioč, Ubavka B. AU - Todorović, Marija R. AU - Jovanović, Tanja AU - Vukojević, Vladana PY - 2006 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/837 AB - Compounds of phosphotungstic acid (WPA) containing the amino acids alanine (WPA-Ala) or glycine (WPA-Gly) as counter cations were synthesized and characterized by elemental analysis, thermal analysis, and IR spectroscopy. Cellular toxicity was assessed by the trypan blue exclusion method, and the antiviral activity of WPA and the modified WPA compounds was tested against herpes simplex viruses (HSV) type 1 and type 2. Biological assays indicate that the newly synthesized compounds exhibit no evident cytotoxic effects on Vero cells and negligible antiviral activity against HSV-1 and HSV-2. PB - Springer Wien, Wien T2 - Monatshefte für Chemie Chemical Monthly T1 - Synthesis, characterization, and biological activity of amino acid derivatives of the heteropolytungstophosphoric acid VL - 137 IS - 6 SP - 803 EP - 810 DO - 10.1007/s00706-006-0467-3 ER -
@article{ author = "Kuntić, Vesna and Stanojević, Maja and Holclajtner-Antunović, Ivanka and Uskoković-Marković, Snežana and Mioč, Ubavka B. and Todorović, Marija R. and Jovanović, Tanja and Vukojević, Vladana", year = "2006", abstract = "Compounds of phosphotungstic acid (WPA) containing the amino acids alanine (WPA-Ala) or glycine (WPA-Gly) as counter cations were synthesized and characterized by elemental analysis, thermal analysis, and IR spectroscopy. Cellular toxicity was assessed by the trypan blue exclusion method, and the antiviral activity of WPA and the modified WPA compounds was tested against herpes simplex viruses (HSV) type 1 and type 2. Biological assays indicate that the newly synthesized compounds exhibit no evident cytotoxic effects on Vero cells and negligible antiviral activity against HSV-1 and HSV-2.", publisher = "Springer Wien, Wien", journal = "Monatshefte für Chemie Chemical Monthly", title = "Synthesis, characterization, and biological activity of amino acid derivatives of the heteropolytungstophosphoric acid", volume = "137", number = "6", pages = "803-810", doi = "10.1007/s00706-006-0467-3" }
Kuntić, V., Stanojević, M., Holclajtner-Antunović, I., Uskoković-Marković, S., Mioč, U. B., Todorović, M. R., Jovanović, T.,& Vukojević, V.. (2006). Synthesis, characterization, and biological activity of amino acid derivatives of the heteropolytungstophosphoric acid. in Monatshefte für Chemie Chemical Monthly Springer Wien, Wien., 137(6), 803-810. https://doi.org/10.1007/s00706-006-0467-3
Kuntić V, Stanojević M, Holclajtner-Antunović I, Uskoković-Marković S, Mioč UB, Todorović MR, Jovanović T, Vukojević V. Synthesis, characterization, and biological activity of amino acid derivatives of the heteropolytungstophosphoric acid. in Monatshefte für Chemie Chemical Monthly. 2006;137(6):803-810. doi:10.1007/s00706-006-0467-3 .
Kuntić, Vesna, Stanojević, Maja, Holclajtner-Antunović, Ivanka, Uskoković-Marković, Snežana, Mioč, Ubavka B., Todorović, Marija R., Jovanović, Tanja, Vukojević, Vladana, "Synthesis, characterization, and biological activity of amino acid derivatives of the heteropolytungstophosphoric acid" in Monatshefte für Chemie Chemical Monthly, 137, no. 6 (2006):803-810, https://doi.org/10.1007/s00706-006-0467-3 . .