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An investigation into the influence of hydrogel composition on swelling behavior and drug release from poly(acrylamide-co-itaconic acid) hydrogels in various media
The hydrogels prepared by free radical copolymerization of acrylamide and itaconic acid were investigated with regard to their composition and crosslinking degree to find materials with satisfactory swelling and drug release properties. Samples were characterized by measuring the swelling behavior and in vitro release of paracetamol as a model drug in aqueous media with different pH values. The two-factor, three-level experimental design and response surface methodology were applied to statistically evaluate the influence of investigated factors.
TY - JOUR
AU - Stanojević, M
AU - Krusić, MK
AU - Filipović, J
AU - Parojčić, Jelena
AU - Stupar, Mirjana
PY - 2006
UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/846
AB - The hydrogels prepared by free radical copolymerization of acrylamide and itaconic acid were investigated with regard to their composition and crosslinking degree to find materials with satisfactory swelling and drug release properties. Samples were characterized by measuring the swelling behavior and in vitro release of paracetamol as a model drug in aqueous media with different pH values. The two-factor, three-level experimental design and response surface methodology were applied to statistically evaluate the influence of investigated factors.
PB - Taylor & Francis Ltd, Abingdon
T2 - Drug Delivery
T1 - An investigation into the influence of hydrogel composition on swelling behavior and drug release from poly(acrylamide-co-itaconic acid) hydrogels in various media
VL - 13
IS - 1
SP - 1
EP - 7
DO - 10.1080/10717540500313034
ER -
@article{
author = "Stanojević, M and Krusić, MK and Filipović, J and Parojčić, Jelena and Stupar, Mirjana",
year = "2006",
abstract = "The hydrogels prepared by free radical copolymerization of acrylamide and itaconic acid were investigated with regard to their composition and crosslinking degree to find materials with satisfactory swelling and drug release properties. Samples were characterized by measuring the swelling behavior and in vitro release of paracetamol as a model drug in aqueous media with different pH values. The two-factor, three-level experimental design and response surface methodology were applied to statistically evaluate the influence of investigated factors.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Drug Delivery",
title = "An investigation into the influence of hydrogel composition on swelling behavior and drug release from poly(acrylamide-co-itaconic acid) hydrogels in various media",
volume = "13",
number = "1",
pages = "1-7",
doi = "10.1080/10717540500313034"
}
Stanojević, M., Krusić, M., Filipović, J., Parojčić, J.,& Stupar, M.. (2006). An investigation into the influence of hydrogel composition on swelling behavior and drug release from poly(acrylamide-co-itaconic acid) hydrogels in various media. in Drug Delivery
Taylor & Francis Ltd, Abingdon., 13(1), 1-7.
https://doi.org/10.1080/10717540500313034
Stanojević M, Krusić M, Filipović J, Parojčić J, Stupar M. An investigation into the influence of hydrogel composition on swelling behavior and drug release from poly(acrylamide-co-itaconic acid) hydrogels in various media. in Drug Delivery. 2006;13(1):1-7.
doi:10.1080/10717540500313034 .
Stanojević, M, Krusić, MK, Filipović, J, Parojčić, Jelena, Stupar, Mirjana, "An investigation into the influence of hydrogel composition on swelling behavior and drug release from poly(acrylamide-co-itaconic acid) hydrogels in various media" in Drug Delivery, 13, no. 1 (2006):1-7,
https://doi.org/10.1080/10717540500313034 . .
