An investigation into the influence of hydrogel composition on swelling behavior and drug release from poly(acrylamide-co-itaconic acid) hydrogels in various media
Abstract
The hydrogels prepared by free radical copolymerization of acrylamide and itaconic acid were investigated with regard to their composition and crosslinking degree to find materials with satisfactory swelling and drug release properties. Samples were characterized by measuring the swelling behavior and in vitro release of paracetamol as a model drug in aqueous media with different pH values. The two-factor, three-level experimental design and response surface methodology were applied to statistically evaluate the influence of investigated factors.
Keywords:
experimental design / hydrogels / paracetamol release / swellingSource:
Drug Delivery, 2006, 13, 1, 1-7Publisher:
- Taylor & Francis Ltd, Abingdon
DOI: 10.1080/10717540500313034
ISSN: 1071-7544
PubMed: 16401587
WoS: 000234467300001
Scopus: 2-s2.0-30644462189
Collections
Institution/Community
PharmacyTY - JOUR AU - Stanojević, M AU - Krusić, MK AU - Filipović, J AU - Parojčić, Jelena AU - Stupar, Mirjana PY - 2006 UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/846 AB - The hydrogels prepared by free radical copolymerization of acrylamide and itaconic acid were investigated with regard to their composition and crosslinking degree to find materials with satisfactory swelling and drug release properties. Samples were characterized by measuring the swelling behavior and in vitro release of paracetamol as a model drug in aqueous media with different pH values. The two-factor, three-level experimental design and response surface methodology were applied to statistically evaluate the influence of investigated factors. PB - Taylor & Francis Ltd, Abingdon T2 - Drug Delivery T1 - An investigation into the influence of hydrogel composition on swelling behavior and drug release from poly(acrylamide-co-itaconic acid) hydrogels in various media VL - 13 IS - 1 SP - 1 EP - 7 DO - 10.1080/10717540500313034 ER -
@article{ author = "Stanojević, M and Krusić, MK and Filipović, J and Parojčić, Jelena and Stupar, Mirjana", year = "2006", abstract = "The hydrogels prepared by free radical copolymerization of acrylamide and itaconic acid were investigated with regard to their composition and crosslinking degree to find materials with satisfactory swelling and drug release properties. Samples were characterized by measuring the swelling behavior and in vitro release of paracetamol as a model drug in aqueous media with different pH values. The two-factor, three-level experimental design and response surface methodology were applied to statistically evaluate the influence of investigated factors.", publisher = "Taylor & Francis Ltd, Abingdon", journal = "Drug Delivery", title = "An investigation into the influence of hydrogel composition on swelling behavior and drug release from poly(acrylamide-co-itaconic acid) hydrogels in various media", volume = "13", number = "1", pages = "1-7", doi = "10.1080/10717540500313034" }
Stanojević, M., Krusić, M., Filipović, J., Parojčić, J.,& Stupar, M.. (2006). An investigation into the influence of hydrogel composition on swelling behavior and drug release from poly(acrylamide-co-itaconic acid) hydrogels in various media. in Drug Delivery Taylor & Francis Ltd, Abingdon., 13(1), 1-7. https://doi.org/10.1080/10717540500313034
Stanojević M, Krusić M, Filipović J, Parojčić J, Stupar M. An investigation into the influence of hydrogel composition on swelling behavior and drug release from poly(acrylamide-co-itaconic acid) hydrogels in various media. in Drug Delivery. 2006;13(1):1-7. doi:10.1080/10717540500313034 .
Stanojević, M, Krusić, MK, Filipović, J, Parojčić, Jelena, Stupar, Mirjana, "An investigation into the influence of hydrogel composition on swelling behavior and drug release from poly(acrylamide-co-itaconic acid) hydrogels in various media" in Drug Delivery, 13, no. 1 (2006):1-7, https://doi.org/10.1080/10717540500313034 . .