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dc.creatorKukić, Jelena
dc.creatorPetrović, Silvana
dc.creatorNiketić, Marjan
dc.date.accessioned2019-09-02T11:08:02Z
dc.date.available2019-09-02T11:08:02Z
dc.date.issued2006
dc.identifier.issn0918-6158
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/865
dc.description.abstractMethanol extracts of aerial flowering parts of four endemic Stachys taxa: S. anisochila Vis. et PANCIC, S. beckeana DORFLER & HAYEK, S. plumosa GRISEB. and S. alpina L. ssp. dinarica MURB. were investigated on their antioxidant activity. The extracts were studied for total antioxidant activity (TAA), along with 1,1-diphenyl 2-picryl hydrazyl (DPPH) and OH radical scavenging activity, and lipid peroxidation (LP). High correlations between total phenolics content, TAA and scavenging DPPH radical indicate that polyphenols are the main antioxidants. All Stachys extracts, with the exception of S. plumosa, exhibited high anti-DPPH activity (IC50 lt 50 mu g/ml). In concentration range from 6.25 to 50 mu g/ml, all extracts scavenged OH radical above 40%, with maximal inhibitions for S. anisochila, S. alpina ssp. dinarica and S. beckeana extracts of 50.22%, 50.94% and 64.97%, respectively. Only S. plumosa extract achieved maximal activity of 60.67% at 100 mu g/ml. As for LP, IC50 values for S. beckeana and S. alpina ssp. dinarica extracts were 25.07 and 49.00 mu g/ml, respectively, while S. anisochila and S. plumosa extracts did not reach 50% of LP inhibition.en
dc.publisherPharmaceutical Soc Japan, Tokyo
dc.rightsopenAccess
dc.sourceBiological & Pharmaceutical Bulletin
dc.subjectStachysen
dc.subjectpolyphenolen
dc.subjectantioxidant activityen
dc.subject1,1-diphenyl 2-picryl hydrazyl (DPPH)en
dc.subjecthydroxyl radicalen
dc.subjectlipid peroxidationen
dc.titleAntioxidant activity of four endemic Stachys taxaen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractНикетић, Марјан; Петровић, Силвана; Кукић, Јелена;
dc.citation.volume29
dc.citation.issue4
dc.citation.spage725
dc.citation.epage729
dc.citation.other29(4): 725-729
dc.citation.rankM23
dc.identifier.wos000237310700022
dc.identifier.doi10.1248/bpb.29.725
dc.identifier.pmid16595907
dc.identifier.scopus2-s2.0-33645552916
dc.identifier.fulltexthttp://farfar.pharmacy.bg.ac.rs//bitstream/id/2227/863.pdf
dc.identifier.rcubconv_1706
dc.type.versionpublishedVersion


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