Due to the favourable health effects of LC n-3 PUFAs, marine products have been recognised as a food group of special importance in the human diet. However, seafood is susceptible to contamination by lipophilic organic pollutants. The objective of this study was to evaluate intake levels of PCDDs, PCDFs and dioxin-like PCBs, by a probabilistic Monte Carlo procedure, in relation to the recommendation on LC n-3 PUFAs given by Belgian Federal Health Council. Regarding the recommendation, two scenarios were developed differing in LC n-3 PUFAs intake: a 0.3 E% and a 0.46 E% scenario. Total exposure to dioxins and dioxin-like substances in the 0.3 E% LC n-3 PUFAs scenario ranges from 2.31 pg TEQ/kg bw/day at the 5th percentile, over 4.37 pg TEQ/kg bw/day at the 50th percentile to 8.41 pg TEQ/kg bw/day at the 95th percentile. In the 0.46 E% LC n-3 PUFAs scenario, 5, 50 and 95th percentile are exposed to 2.74, 5.52 and 9.98 pg TEQ/kg bw/day, respectively. Therefore, if the recommended LC n-3 P...UFAs intake would be based on fish consumption as the only extra source, the majority of the study population would exceed the proposed health based guidance values for dioxins and dioxin-like substances.
TY - JOUR
AU - Antonijević, Biljana
AU - Matthys, C.
AU - Sipes, I.G
AU - Bilau, M.
AU - Van Camp, J.
AU - Willems, J. L.
AU - De Henauw, S.
PY - 2007
UR - https://farfar.pharmacy.bg.ac.rs/handle/123456789/889
AB - Due to the favourable health effects of LC n-3 PUFAs, marine products have been recognised as a food group of special importance in the human diet. However, seafood is susceptible to contamination by lipophilic organic pollutants. The objective of this study was to evaluate intake levels of PCDDs, PCDFs and dioxin-like PCBs, by a probabilistic Monte Carlo procedure, in relation to the recommendation on LC n-3 PUFAs given by Belgian Federal Health Council. Regarding the recommendation, two scenarios were developed differing in LC n-3 PUFAs intake: a 0.3 E% and a 0.46 E% scenario. Total exposure to dioxins and dioxin-like substances in the 0.3 E% LC n-3 PUFAs scenario ranges from 2.31 pg TEQ/kg bw/day at the 5th percentile, over 4.37 pg TEQ/kg bw/day at the 50th percentile to 8.41 pg TEQ/kg bw/day at the 95th percentile. In the 0.46 E% LC n-3 PUFAs scenario, 5, 50 and 95th percentile are exposed to 2.74, 5.52 and 9.98 pg TEQ/kg bw/day, respectively. Therefore, if the recommended LC n-3 PUFAs intake would be based on fish consumption as the only extra source, the majority of the study population would exceed the proposed health based guidance values for dioxins and dioxin-like substances.
PB - Pergamon-Elsevier Science Ltd, Oxford
T2 - Food and Chemical Toxicology
T1 - Simulated impact of a fish based shift in the population n-3 fatty acids intake on exposure to dioxins and dioxin-like compounds
VL - 45
IS - 11
SP - 2279
EP - 2286
DO - 10.1016/j.fct.2007.06.003
ER -
@article{
author = "Antonijević, Biljana and Matthys, C. and Sipes, I.G and Bilau, M. and Van Camp, J. and Willems, J. L. and De Henauw, S.",
year = "2007",
abstract = "Due to the favourable health effects of LC n-3 PUFAs, marine products have been recognised as a food group of special importance in the human diet. However, seafood is susceptible to contamination by lipophilic organic pollutants. The objective of this study was to evaluate intake levels of PCDDs, PCDFs and dioxin-like PCBs, by a probabilistic Monte Carlo procedure, in relation to the recommendation on LC n-3 PUFAs given by Belgian Federal Health Council. Regarding the recommendation, two scenarios were developed differing in LC n-3 PUFAs intake: a 0.3 E% and a 0.46 E% scenario. Total exposure to dioxins and dioxin-like substances in the 0.3 E% LC n-3 PUFAs scenario ranges from 2.31 pg TEQ/kg bw/day at the 5th percentile, over 4.37 pg TEQ/kg bw/day at the 50th percentile to 8.41 pg TEQ/kg bw/day at the 95th percentile. In the 0.46 E% LC n-3 PUFAs scenario, 5, 50 and 95th percentile are exposed to 2.74, 5.52 and 9.98 pg TEQ/kg bw/day, respectively. Therefore, if the recommended LC n-3 PUFAs intake would be based on fish consumption as the only extra source, the majority of the study population would exceed the proposed health based guidance values for dioxins and dioxin-like substances.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Food and Chemical Toxicology",
title = "Simulated impact of a fish based shift in the population n-3 fatty acids intake on exposure to dioxins and dioxin-like compounds",
volume = "45",
number = "11",
pages = "2279-2286",
doi = "10.1016/j.fct.2007.06.003"
}
Antonijević, B., Matthys, C., Sipes, I.G, Bilau, M., Van Camp, J., Willems, J. L.,& De Henauw, S.. (2007). Simulated impact of a fish based shift in the population n-3 fatty acids intake on exposure to dioxins and dioxin-like compounds. in Food and Chemical Toxicology
Pergamon-Elsevier Science Ltd, Oxford., 45(11), 2279-2286.
https://doi.org/10.1016/j.fct.2007.06.003
Antonijević B, Matthys C, Sipes I, Bilau M, Van Camp J, Willems JL, De Henauw S. Simulated impact of a fish based shift in the population n-3 fatty acids intake on exposure to dioxins and dioxin-like compounds. in Food and Chemical Toxicology. 2007;45(11):2279-2286.
doi:10.1016/j.fct.2007.06.003 .
Antonijević, Biljana, Matthys, C., Sipes, I.G, Bilau, M., Van Camp, J., Willems, J. L., De Henauw, S., "Simulated impact of a fish based shift in the population n-3 fatty acids intake on exposure to dioxins and dioxin-like compounds" in Food and Chemical Toxicology, 45, no. 11 (2007):2279-2286,
https://doi.org/10.1016/j.fct.2007.06.003 . .
