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dc.creatorAntonijević, Biljana
dc.creatorMatthys, C.
dc.creatorSipes, I.G
dc.creatorBilau, M.
dc.creatorVan Camp, J.
dc.creatorWillems, J. L.
dc.creatorDe Henauw, S.
dc.date.accessioned2019-09-02T11:08:41Z
dc.date.available2019-09-02T11:08:41Z
dc.date.issued2007
dc.identifier.issn0278-6915
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/889
dc.description.abstractDue to the favourable health effects of LC n-3 PUFAs, marine products have been recognised as a food group of special importance in the human diet. However, seafood is susceptible to contamination by lipophilic organic pollutants. The objective of this study was to evaluate intake levels of PCDDs, PCDFs and dioxin-like PCBs, by a probabilistic Monte Carlo procedure, in relation to the recommendation on LC n-3 PUFAs given by Belgian Federal Health Council. Regarding the recommendation, two scenarios were developed differing in LC n-3 PUFAs intake: a 0.3 E% and a 0.46 E% scenario. Total exposure to dioxins and dioxin-like substances in the 0.3 E% LC n-3 PUFAs scenario ranges from 2.31 pg TEQ/kg bw/day at the 5th percentile, over 4.37 pg TEQ/kg bw/day at the 50th percentile to 8.41 pg TEQ/kg bw/day at the 95th percentile. In the 0.46 E% LC n-3 PUFAs scenario, 5, 50 and 95th percentile are exposed to 2.74, 5.52 and 9.98 pg TEQ/kg bw/day, respectively. Therefore, if the recommended LC n-3 PUFAs intake would be based on fish consumption as the only extra source, the majority of the study population would exceed the proposed health based guidance values for dioxins and dioxin-like substances.en
dc.publisherPergamon-Elsevier Science Ltd, Oxford
dc.rightsrestrictedAccess
dc.sourceFood and Chemical Toxicology
dc.subjectfishen
dc.subjectomega-3 PUFAsen
dc.subjectPCDDsen
dc.subjectPCDFsen
dc.subjectdioxin-like PCBsen
dc.subjectprobabilistic modellingen
dc.titleSimulated impact of a fish based shift in the population n-3 fatty acids intake on exposure to dioxins and dioxin-like compoundsen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractWиллемс, Ј. Л.; Де Хенауw, С.; Сипес, И.Г; Билау, М.; Маттхyс, Ц.; Aнтонијевић, Биљана; Ван Цамп, Ј.;
dc.citation.volume45
dc.citation.issue11
dc.citation.spage2279
dc.citation.epage2286
dc.citation.other45(11): 2279-2286
dc.citation.rankM21
dc.identifier.wos000251014400022
dc.identifier.doi10.1016/j.fct.2007.06.003
dc.identifier.pmid17637492
dc.identifier.scopus2-s2.0-34648820639
dc.identifier.rcubconv_1927
dc.type.versionpublishedVersion


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