FarFaR - Pharmacy Repository
University of Belgrade, Faculty of Pharmacy
    • English
    • Српски
    • Српски (Serbia)
  • English 
    • English
    • Serbian (Cyrillic)
    • Serbian (Latin)
  • Login
View Item 
  •   FarFaR
  • Pharmacy
  • Radovi istraživača / Researchers’ publications
  • View Item
  •   FarFaR
  • Pharmacy
  • Radovi istraživača / Researchers’ publications
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Compounds of Mo, V and W in biochemistry and their biomedical activity

Authorized Users Only
2007
Authors
Jelikić-Stankov, Milena
Uskoković-Marković, Snežana
Holclajtner-Antunović, Ivanka
Todorović, Marija R.
Đurđević, Predrag
Article (Published version)
Metadata
Show full item record
Abstract
Molybdenum, vanadium and tungsten compounds are widely applied as analytical reagents for determination of numerous pharmacologically active substances and different biochemical parameters. Recent data from the available literature pointed to a very potent biomedical activity of compounds containing these trace elements. The present paper represents a survey on the structure and chemical properties of these compounds, as well as on their biological activity, mostly based on their interaction with cations of biomolecules, such as phospholipids and proteins. Besides, their potent inhibitory effects on cellular targets, bacterial and viral DNA and RNA polymerases will be discussed, as well. Numerous authors clearly demonstrated the antiviral (especially anti-HIV), anticoagulant and antineoplastic properties of the compounds containing the above trace elements. It has been also shown that these compounds act on some cellular enzymatic systems leading to the normalisation of blood pressure,... blood glucose and serum lipid levels. Also, compounds of these trace elements represent potent antiobesity agents and express hepatoprotective and antioxidative stress activity.

Keywords:
molybdenum / vanadium / tungsten / biomedical activity
Source:
Journal of Trace Elements in Medicine and Biology, 2007, 21, 1, 8-16
Publisher:
  • Elsevier Gmbh, Urban & Fischer Verlag, Jena
Funding / projects:
  • Bioaktivni kompleksi p i d jona metala sa ligandima farmakoterapijskog značaja (RS-142013)
  • Struktura, termodinamičke i elektrohemijske osobine materijala za konverziju energije i nove tehnologije (RS-142047)

DOI: 10.1016/j.jtemb.2006.11.004

ISSN: 0946-672X

PubMed: 17317520

WoS: 000245350300002

Scopus: 2-s2.0-33847195018
[ Google Scholar ]
42
34
URI
https://farfar.pharmacy.bg.ac.rs/handle/123456789/912
Collections
  • Radovi istraživača / Researchers’ publications
Institution/Community
Pharmacy
TY  - JOUR
AU  - Jelikić-Stankov, Milena
AU  - Uskoković-Marković, Snežana
AU  - Holclajtner-Antunović, Ivanka
AU  - Todorović, Marija R.
AU  - Đurđević, Predrag
PY  - 2007
UR  - https://farfar.pharmacy.bg.ac.rs/handle/123456789/912
AB  - Molybdenum, vanadium and tungsten compounds are widely applied as analytical reagents for determination of numerous pharmacologically active substances and different biochemical parameters. Recent data from the available literature pointed to a very potent biomedical activity of compounds containing these trace elements. The present paper represents a survey on the structure and chemical properties of these compounds, as well as on their biological activity, mostly based on their interaction with cations of biomolecules, such as phospholipids and proteins. Besides, their potent inhibitory effects on cellular targets, bacterial and viral DNA and RNA polymerases will be discussed, as well. Numerous authors clearly demonstrated the antiviral (especially anti-HIV), anticoagulant and antineoplastic properties of the compounds containing the above trace elements. It has been also shown that these compounds act on some cellular enzymatic systems leading to the normalisation of blood pressure, blood glucose and serum lipid levels. Also, compounds of these trace elements represent potent antiobesity agents and express hepatoprotective and antioxidative stress activity.
PB  - Elsevier Gmbh, Urban & Fischer Verlag, Jena
T2  - Journal of Trace Elements in Medicine and Biology
T1  - Compounds of Mo, V and W in biochemistry and their biomedical activity
VL  - 21
IS  - 1
SP  - 8
EP  - 16
DO  - 10.1016/j.jtemb.2006.11.004
ER  - 
@article{
author = "Jelikić-Stankov, Milena and Uskoković-Marković, Snežana and Holclajtner-Antunović, Ivanka and Todorović, Marija R. and Đurđević, Predrag",
year = "2007",
abstract = "Molybdenum, vanadium and tungsten compounds are widely applied as analytical reagents for determination of numerous pharmacologically active substances and different biochemical parameters. Recent data from the available literature pointed to a very potent biomedical activity of compounds containing these trace elements. The present paper represents a survey on the structure and chemical properties of these compounds, as well as on their biological activity, mostly based on their interaction with cations of biomolecules, such as phospholipids and proteins. Besides, their potent inhibitory effects on cellular targets, bacterial and viral DNA and RNA polymerases will be discussed, as well. Numerous authors clearly demonstrated the antiviral (especially anti-HIV), anticoagulant and antineoplastic properties of the compounds containing the above trace elements. It has been also shown that these compounds act on some cellular enzymatic systems leading to the normalisation of blood pressure, blood glucose and serum lipid levels. Also, compounds of these trace elements represent potent antiobesity agents and express hepatoprotective and antioxidative stress activity.",
publisher = "Elsevier Gmbh, Urban & Fischer Verlag, Jena",
journal = "Journal of Trace Elements in Medicine and Biology",
title = "Compounds of Mo, V and W in biochemistry and their biomedical activity",
volume = "21",
number = "1",
pages = "8-16",
doi = "10.1016/j.jtemb.2006.11.004"
}
Jelikić-Stankov, M., Uskoković-Marković, S., Holclajtner-Antunović, I., Todorović, M. R.,& Đurđević, P.. (2007). Compounds of Mo, V and W in biochemistry and their biomedical activity. in Journal of Trace Elements in Medicine and Biology
Elsevier Gmbh, Urban & Fischer Verlag, Jena., 21(1), 8-16.
https://doi.org/10.1016/j.jtemb.2006.11.004
Jelikić-Stankov M, Uskoković-Marković S, Holclajtner-Antunović I, Todorović MR, Đurđević P. Compounds of Mo, V and W in biochemistry and their biomedical activity. in Journal of Trace Elements in Medicine and Biology. 2007;21(1):8-16.
doi:10.1016/j.jtemb.2006.11.004 .
Jelikić-Stankov, Milena, Uskoković-Marković, Snežana, Holclajtner-Antunović, Ivanka, Todorović, Marija R., Đurđević, Predrag, "Compounds of Mo, V and W in biochemistry and their biomedical activity" in Journal of Trace Elements in Medicine and Biology, 21, no. 1 (2007):8-16,
https://doi.org/10.1016/j.jtemb.2006.11.004 . .

DSpace software copyright © 2002-2015  DuraSpace
About FarFaR - Pharmacy Repository | Send Feedback

OpenAIRERCUB
 

 

All of DSpaceCommunitiesAuthorsTitlesSubjectsThis institutionAuthorsTitlesSubjects

Statistics

View Usage Statistics

DSpace software copyright © 2002-2015  DuraSpace
About FarFaR - Pharmacy Repository | Send Feedback

OpenAIRERCUB