Antidepressants and anxiolytics: Novel tablet formulations

Abstract

Development of new dosage forms with uncompromised efficacy, safety and stability and improved tolerability and dosage regimen that would result in better patient compliance is an imperative in modern pharmacotherapy. Patients" adherence to dosage regimen is of great importance, especially when prolonged treatment is an issue. Therefore, novelties in formulation development for antidepressants and anxiolytics are directed towards the modified/sustained or extended release drug products and orally disintegrating tablets. There is a number and variety of new technologies employed with this respect. In the present paper, an overview of the most important technologies applied in commercially available drug products within the group of antidepressants and anxiolytics is given.