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dc.creatorAntić, Dušan
dc.creatorFilipić, Slavica
dc.creatorAgbaba, Danica
dc.date.accessioned2019-09-02T11:10:48Z
dc.date.available2019-09-02T11:10:48Z
dc.date.issued2007
dc.identifier.issn1233-2356
dc.identifier.urihttps://farfar.pharmacy.bg.ac.rs/handle/123456789/970
dc.description.abstractA simple, conventional TLC method has been established for separation of clopidogrel and its hydrolytic product SR 26334, the main impurity in clopidogrel. Use of aluminium. foil-backed silica gel 60F(254) plates with n-heptane-tetrahydrofuran, 1:1 (v/v), as mobile phase, enabled successful separation of clopidogrel in high excess from the impurity. The separated compounds were detected at 230 nm. Regession coefficients (r >= 0.999), recovery (94.5-107.1%), and limit of quantification (0.047 mg mL(-1)) were evaluated and found to be satisfactory. The method is convenient for quantitative analysis and purity control of clopidogrel both in raw material and in dosage forms.en
dc.publisherUniv Silesia, Inst Chemistry, Katowice
dc.rightsrestrictedAccess
dc.sourceActa Chromatographica
dc.titleA simple and sensitive TLC method for determination of clopidogrel and its impurity SR 26334 in pharmaceutical productsen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractФилипић, Славица; Aнтић, Д.; Aгбаба, Даница;
dc.citation.volume18
dc.citation.spage199
dc.citation.epage206
dc.citation.other18: 199-206
dc.citation.rankM23
dc.identifier.wos000249705200017
dc.identifier.scopus2-s2.0-34548263684
dc.identifier.rcubhttps://hdl.handle.net/21.15107/rcub_farfar_970
dc.type.versionpublishedVersion


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